Celiac disease

Psoriasis and Celiac Disease – Genetic Link

The research below further supports the links demonstrated between celiac disease and psoriasis as noted in the book “Recognizing Celiac Disease.” (www.recognizingceliacdisease.com) Although not the focus of this study, the link could be a genetic sensitivity to gluten itself, considering the resolution of symptoms seen by people with psoriasis who go on a gluten-free diet. In addition, the other disorders, diabetes type 1 and arthritis have been linked to celiac disease/gluten sensitivity reactions. – John Libonati, Glutenfreeworks.com

Psoriasis: 7 New Genetic Clues

Newly Discovered Genetic Variations May Make Psoriasis More Likely, Study Shows
By Miranda Hitti

WebMD Medical NewsReviewed by Louise Chang, MDApril 3, 2008 — Scientists have discovered seven genetic variations linked to psoriasis.

If confirmed in other studies, those gene variants may make good targets for new psoriasis drugs, note the researchers, who included Anne Bowcock, PhD, genetics professor at Washington University School of Medicine in St. Louis.

“Common diseases like psoriasis are incredibly complex at the genetic level,” Bowcock says in a news release. “Our research shows that small but common DNA differences are important in the development of psoriasis. Although each variation makes only a small contribution to the disease, patients usually have a number of different genetic variations that increases their risk of psoriasis and psoriatic arthritis.”

Bowcock’s team compared DNA from 223 psoriasis patients (including 91 with psoriatic arthritis) and 519 people without psoriasis, and also from two other large groups of people with and without psoriasis.

Through those comparisons, the researchers identified seven genetic variations linked to psoriasis and psoriatic arthritis and confirmed other variations already linked to psoriasis.

One of the newly discovered variants is in a genetic region tied to four other autoimmune diseases: celiac disease, type 1 diabetes, Grave’s disease, and rheumatoid arthritis.

Further studies are needed to confirm the findings, Bowcock and colleagues note in the April 4 online edition of Public Library of Science Genetics.

View Article Sources
SOURCES:

Liu, Y. Public Library of Science Genetics, April 4, 2008; online edition.

News release, Public Library of Science.

© 2008 WebMD, LLC. All rights reserved.
http://www.webmd.com:80/skin-problems-and-treatments/psoriasis/news/20080403/psoriasis-7-new-genetic-clues

Psoriasis and Celiac Disease – Genetic Link

Reprinted from April 4, 2008

Editors Note: The research below further supports the links demonstrated between celiac disease and psoriasis as described in the book “Recognizing Celiac Disease.”  Although not the focus of this study, the link could be a genetic sensitivity to gluten itself, considering the resolution of symptoms seen by people with psoriasis who go on a gluten-free diet. In addition, the other disorders, diabetes type 1 and arthritis have been linked to celiac disease/gluten sensitivity reactions.

 

 

psoriasis and celiac disease

Psoriasis on back, Courtesy Wikimedia

“Psoriasis: 7 New Genetic Clues”

 

Newly Discovered Genetic Variations May Make Psoriasis More Likely, Study Shows
By Miranda Hitti

WebMD Medical NewsReviewed by Louise Chang, MDApril 3, 2008 — Scientists have discovered seven genetic variations linked to psoriasis. Read More »

Quinoa Pizza Bites Recipe

I must preface this recipe with the fact that up until this point, I did not think I liked quinoa. The main reason for my dislike of this seed was that I had a poorly prepared dish with it last year and thought that no matter what, the little gluten-free gems could never taste good. Welp folks, I was wrong. This easy quinoa recipe can be used as an alternative to gluten-free pizza dough and will rock your taste-bud’s world.BitesServing

Quinoa Pizza Bites

 

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Rachel Lu Muffins: Truly Homemade

Heading back to school means one thing when you are on a restricted diet: stock up on all your favorites which you can’t find at school. This break I didn’t do much shopping or searching for new products, instead I ate less process foods and stayed away from sandwiches. This resulted in me feeling much better. Read More »

Reality TV Shows are Including the Reality of Celiac Disease

trumppic

By Nancy Lapid, About.com Guide to Celiac Disease

Celiac disease has been a topic on not one but two TV shows in the past few days. I hardly watch television, so I’m fortunate to have learned about these episodes from a fellow blogger, the Gluten-Free Optimist.
First, the cable network BBC America’s reality show Last Restaurant Standing had an episode (#13) in which competing restauranteurs were required to come up with food for celiac guests (and other “tricky customers”) without advance warning. This episode will be replayed; the schedule is posted on the BBC America site. Read More »

Research Study on Genetic Testing Looking for Survey Participants

Gluten Free Works Jennifer Harris

Columbia University Celiac Disease Center

The Celiac Disease Center at Columbia University invites you to participate in a research study looking at individuals’ knowledge of genetic testing of celiac disease and their potential concerns with such testing.  The goal of this study is to increase understanding of the factors associated with making an informed decision regarding such testing and to better provide the necessary information to make such a decision.

A brief survey has been developed to address some of these factors.  The survey only takes five minutes to complete, it is anonymous, and no identifying information is collected. 
 
If you or a family member has celiac disease or gluten sensitivity, Read More »

Researchers Develop A Faster Way To Diagnose Celiac Disease

John Libonati Gluten Free Works

The following article was written by Erika Gebel and reprinted by permision from Chemical and Engineering News.

Celiac Disease Gluten Sensitivity Test

Celiac Disease and Gluten Sensitivity Often Go Undiagnosed

Judging by their symptoms, people with celiac disease could have food poisoning, depression, or iron deficiency. As a result, doctors often have trouble diagnosing the serious immune disorder. To develop a better test for the disease, researchers have made a device that can detect nanograms of gluten antibodies, the hallmarks of celiac disease, in human Read More »

Researchers Seeking Adults with Celiac Disease

Adults that have been diagnosed with Celiac Disease are being sought to participate in a study to identify factors associated with the development of Celiac Disease.  The goal of the study is to find the genes that may predispose individuals to develop this autoimmune disease.  Adults eligible to participate in this study must have been diagnosed with Celiac Disease through a small intestinal biopsy. Spouses may also be eligible to participate.

Participants will be asked to provide a blood sample, complete a questionnaire, and provide medical records regarding their diagnosis. There is no cost to Read More »

Restless Leg Syndrome, Celiac Disease & Improvement on the Gluten Free Diet

 

restless leg syndrome treatment

RLS from low iron in celiac disease responds to a gluten-free diet

Low iron levels have been associated with increased severity of restless leg syndrome. The following medical case report discusses four patients with low iron and restless leg syndrome who were tested positive for celiac disease and placed on a gluten free diet. All four had improvement on the gluten free diet.

“Celiac disease as a Possible Cause for Low Serum Ferritin in Patients with Restless Legs Syndrome.”

Manchanda S, Davies CR, Picchietti D.

University of Illinois at Urbana-Champaign, College of Medicine, 506 S. Mathews Avenue, Suite 190, Urbana, IL 61801, USA.

OBJECTIVE: To describe celiac disease as a possible cause for low serum ferritin in patients with restless legs syndrome (RLS). BACKGROUND: Low iron stores have been found to be a risk factor for RLS with serum ferritin levels less than 45-50ng/mL associated with increased severity of RLS. It has become routine clinical practice to test serum ferritin in the initial assessment of RLS. Celiac disease is a common genetic disorder that can cause iron deficiency.

METHODS: Consecutive case series of four patients with RLS and serum ferritin below 25ng/mL, who had positive screening tests for celiac disease. RESULTS: We report four patients who had serum ferritin <12ng/mL and positive screening tests for celiac disease. All had celiac disease confirmed by duodenal biopsy and response to a gluten-free diet. RLS symptoms improved in all four, with two able to discontinue RLS medication and two responding without medication.

CONCLUSIONS: In patients with RLS and low serum ferritin who do not have an obvious cause for iron deficiency, we suggest looking for celiac disease by simple, inexpensive serologic testing. Diagnosis and treatment of celiac disease is likely to improve the outcome for RLS, as well as identify individuals who are at risk for the significant long-term complications of celiac disease.

Source: Sleep Med. 2009 Jan 10. [Epub ahead of print] url: http://www.ncbi.nlm.nih.gov/pubmed/19138881

Santa Hat Cupcakes

gluten free Christmas cupcakes

Santa Hat Cupcakes courtesy of Lauryn Cohen

I know you might think I’m clever, but really, I’m not. Full credit goes to Lauryn Cohen, aka Bella Baker, who came up with this cute concept. Lauren is the queen of sweet and is known for her uniquely creative treats and crafts. She recently launched a holiday baking guide (entitled Sweet Gifts Holiday Baking and Crafting Guide– available nationwide) filled with innovative and delicious recipes for the holidays.

Lauryn was nice enough to share one of her creations with The Family Chef. In this recipe, she calls for a red velvet cupcake (you will find a gluten-free, no-dye recipe in my upcoming cookbook). You can always use a basic vanilla (gluten-free).

Here is her technique for making super cute holiday cupcakes for your friends or family. Read More »

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