Celiac disease

 Editors’ note: This study investigating the value and safety of Candin for clinical use in children demonstrated effectiveness and safety.  Candin is a reagent or skin test for sensitivity to Candida albicans, a yeast microorganism that can cause infection.  The study recommends using Candin in combination with other reagents in infants with anergy to see if they react to antigens other than Candida albicans.  Anergy is described in Taber’s Cyclopedic Medical Dictionary as the impaired or absent ability to react to common antigens administered through skin testing. Antigens are markers on the surface of cells that stimulate production of antibodies.  In this study, Candin was tested at the same time as a skin test for tuberculosis (purified protein derivative tuberculosis) for comparison of results. Read More »

Riboflavin is a micronutrient, also known as Vitamin B2, which performs many important functions in the body. Riboflavin is a water-soluble vitamin that releases energy from carbohydrates, amino acids, and lipids. It plays a key role in specific amino acid production and provides antioxidant protection. Riboflavin is essential for growth and production of red blood cells and maintaining healthy skin, eyes, hair, and nervous system.

Riboflavin Deficiency

More than 34% of Americans get less than the RDA because, unlike other vitamins, riboflavin is not found in many foods.

Riboflavin depletion and/or deficiency is common before starting the gluten-free diet treatment. It frequently results from malabsorption due to damage to the small intestinal lining, but can also be depleted by excretion through diarrhea, excessive sweating or excessive urination. It is important to note that riboflavin deficiency can result from low serum proteins, which is a common occurrence in untreated celiac disease.

When riboflavin deficiency appears after starting the gluten-free diet, it is usually due to Read More »

According to the National Digestive Diseases Information Clearing House, a study published in the December 2008 issue of the Journal of Insurance Medicine reports that researchers from Columbia University and CIGNA HealthCare found that diagnosis of celiac disease substantially reduces subsequent health care costs. 

The research group, led by Peter Green, M.D., a renowned authority in celiac disease from Columbia University,  looked at medical records for 10.2 million CIGNA managed care members.   Read More »

 3 06 08

Contact: Sally Webster
s.webster@qmul.ac.uk
44-207-882-5404
Queen Mary, University of London

Scientists who last year identified a new genetic risk factor for coeliac disease, have, following continued research, discovered an additional seven gene regions implicated in causing the condition. The team, lead by David van Heel, Professor of Gastrointestinal Genetics at Barts and The London School of Medicine and Dentistry, have further demonstrated that of the nine coeliac gene regions now know, four of these are also predisposing factors for type 1 diabetes. Their research sheds light not only on the nature of coeliac disease, but on the common origins of both diseases. It is published online today (2 March 2008) in Nature Genetics. Read More »

Copper usually receives little coverage, but this unpretentious nutrient deserves center stage.  It is time for a serious role review.

Here are two reasons: First, deficiency of this trace mineral can debilitate and threaten our lives, and second, deficiency develops with increased frequency in those of us with celiac disease, unlike the general population.

Copper plays a critical role in the formation of a variety of proteins and enzymes involved in functions that keep us alive. Consequently, many disorders caused by copper deficiency stem from failure to adequately produce or release copper proteins and enzymes. Read More »

ScienceDaily (July 22, 2010) — Walter and Eliza Hall Institute scientists have identified the three protein fragments that make gluten — the main protein in wheat, rye and barley — toxic to people with coeliac disease.

Professor Bob Anderson from the Walter and Eliza Hall Institute in Melbourne, Australia, has identified the three protein fragments that make gluten -- the main protein in wheat, rye and barley -- toxic to people with celiac disease. (Credit: Czesia Markiewicz, Walter and Eliza Hall Institute)

Their discovery opens the way for a new generation of diagnostics, treatments, prevention strategies and food tests for the millions of people worldwide with coeliac disease.

When people with coeliac disease eat products containing gluten their body’s immune response is switched on and the lining of the small intestine is damaged, hampering their ability to absorb nutrients. The disease is currently treated by permanently removing gluten from the patient’s diet.

Dr Bob Anderson, head of the Walter and Eliza Hall Institute’s coeliac disease research laboratory, said it had been 60 years since gluten was discovered to be the environmental cause of coeliac disease.

“In the years since, the holy grail in coeliac disease research has been to identify the toxic peptide components of gluten; and that’s what we’ve done,” Dr Anderson said.

The research, done in collaboration with Dr Jason Tye-Din, Dr James Dromey, Dr Stuart Mannering, Dr Jessica Stewart and Dr Tim Beissbarth from the institute as well as Professor Jamie Rossjohn at Monash University and Professor Jim McCluskey at the University of Melbourne, is published in the journalScience Translational Medicine.

Dr. Bob Anderson & John Libonati at an NFCA-sponsored event April 30, 2009 in Philadelphia, USA where Dr. Anderson described his research and vaccine.

The study was started by Professor Anderson nine years ago and has involved researchers in Australia and the UK as well as more than 200 coeliac disease patients.

The patients, recruited through the Coeliac Society of Victoria and the Coeliac Clinic at John Radcliffe Hospital, UK, ate bread, rye muffins or boiled barley. Six days later, blood samples were taken to measure the strength of the patients’ immune responses to 2700 different gluten fragments. The responses identified 90 fragments as causing some level of immune reaction, but three gluten fragments (peptides) were revealed as being particularly toxic.

“These three components account for the majority of the immune response to gluten that is observed in people with coeliac disease,” Dr Anderson said. Read More »

As baby boomers segue from child-rearing to retirement, they find themselves bombarded by the media with information about osteoporosis. It makes sense, considering that more than 44 million American men and women age 50 and older have osteoporosis or its precursor, osteopenia. So between news articles about calcium and vitamin D, Sally Field promoting the drug Boniva on TV commercials and the now-ubiquitous term “weight-bearing exercise,” we are all hearing a great deal about this epidemic.

Yet controversy abounds, with new findings questioning the benefits of calcium as well as the risks versus benefits of osteoporosis medications. The conflicting information is enough to overwhelm even the most media-savvy consumer. But the one continuously advocated method of addressing the condition is exercise. Not only does exercise help to maintain and build strong bones, but it can improve balance and reflexes and thereby prevent falls, the most dangerous threat to those with fragile bones. According to the International Osteoporosis Foundation, 60 percent of those who fracture a hip still cannot walk independently a year later. Clearly, the goal should be to stay strong, agile and upright. Read More »

Hey guys! I just found a great health email I think all those interested in the particulars of health and current research would be really interested in. 

Harvard Health Publications

In particular, there is a great, informative and interesting article on the rise of gluten sensitivities and Celiac disease. You might have to sign up for the email newsletter to see it, but I think it’s worth it. 

The article goes into detail on various elements concerning gluten digestive issues such as; understanding what happens within the body in regards to gluten absorption, common and uncommon symptoms, testing to diagnose Celiac, and the “Super Six”, explained further in the quote below:  Read More »

The mineral zinc is classified as an essential nutrient due to the vital functions it performs in our bodies.  It is found in almost every cell of the body with highest concentrations in the liver, pancreas, kidney, bone, and muscle. High concentrations occur in the brain, middle ear, eye, prostate gland, sperm, skin, hair, and nails. This micronutrient is essential for the activity of approximately 100 enzymes. Enzymes promote biochemical reactions in the body.

Zinc supports a healthy immune system. It is needed for wound healing and DNA synthesis. It helps maintain our sense of taste and smell and is involved in energy metabolism, hemoglobin production, carbon dioxide transport, prostaglandin function, synthesis of collagen, protein synthesis, and vitamin A metabolism. Zinc is important for male fertility. It supports normal growth and development during pregnancy, childhood, and adolescence. Read More »

Vitamin A was first identified in 1913 because of its crucial role in vision.  Subsequent discovery of its many other duties show that a deficiency will cause a broad range of health problems.

Vitamin A is not a single compound but actually comprises a fat-soluble family of molecules that includes retinol, retinal, retinoic acid, and retinyl ester. The term vitamin A also includes certain plant carotenoids called provitamin A because they are dietary precursors of retinol.

Vitamin A is essential for normal vision and eyeball health, a properly functioning immune system, gene regulation, reproduction, embryonic development, health and protection of all the tissues that line the body, including skin and mucosa of the lungs, digestive tract, urinary tract, and genital tract, bone metabolism and normal growth and strong teeth in children.

Vitamin A Deficiency

The United States National Institutes of Health recommends testing vitamin A levels in people with celiac disease at diagnosis. This is because vitamin A deficiency is common in celiac disease. Deficiency can result from incomplete digestion, absorption, or metabolism. Read More »