Treatment Guide

Investigation of Gluten Sensitivity Requires Anti-Gliadin Antibody Testing

[Editor’s Note: Reprinted from 7 09 08 – and still very important.]

antibody and antigen gluten sensitivity

Author: Fvasconcellos Source: Wikimedia Commons

The news release below is timely because anti-gliadin antibody blood tests are losing ground while the reality of gluten sensitivity looms far larger than is now appreciated by many doctors!  These blood tests are absolutely necessary to investigate health problems caused by gluten itself, yet they are being dismissed by doctors who look only to diagnosing celiac disease.

Positive anti-gliadin antibody tests show undigested gluten peptides in the bloodstream.  This abnormal finding tells the story that gluten has passed through the tight barrier defenses of the small intestinal lining into the body where it can wreak havoc, with or without celiac disease.  Gluten is a food protein in wheat, barley, rye and oats.

In screening for celiac disease, an inherited immune response to gluten entering the small intestinal lining, doctors rely on the celiac specific antibody tests, anti-endomysium and anti-tissue transglutaminase.  However, the investigation to find these auto-antibodies must not exclude the anti-gliadin antibodies.

“Doctors Slow To Recognise Gluten Harm.” Dr. Rodney Ford, Leading New Zealand Paediatrician And Allergist Challenges Medical Stalwarts With Revolutionary Gluten Thinking

There is more to gluten problems than just coeliac disease. Gluten sensitivity is ten times more prevalent than celiac disease in New Zealand and mostly undiagnosed. This is the message that Christchurch-based paediatrician, allergist and author, Doctor Rodney Ford wants to get across to the public and the ever conservative medical fraternity.

The practice of medicine is restricted to the knowledge, experience, attitudes and politics of the society it functions in. Medicine is an inexact but evolving science, thus current standard medical practices are often disproved. The validity of medical opinion, long held to be the gold standard of diagnosis and treatment, are constantly challenged. This is a healthy dynamic, one that enables the pursuit of excellence and the evolution of better forms of practice, resulting in better outcomes for patients. Why, then asks Dr Ford, is there such resistance to his new Gluten Syndrome hypothesis recently published in a book and supported by years of clinical experience and research.

In the absence of coeliac disease, his latest research shows that the simple gluten test (IgG-gliadin antibody) is a sensitive indicator to detect those people who get sick eating gluten but who have tested negative to Celiac Disease. However, this test is rarely ordered by general practitioners or specialists. He says “This is because of an illogical rejection of gluten sensitivity as a valid diagnosis. Ignoring gluten flies in the face of all of the evidence and is also alienating doctors from their patients.”

Picture this, if you will: a six year old girl, Elizabeth, small for her age, a distended stomach, gas and suffering from gastric reflux. Her teachers reported a lack of attention at school and early learning problems. Elizabeth had been thoroughly investigated by the medical profession: blood tests, bowel biopsies, colonoscopy, endoscopy. Celiac Disease had been ruled out, various medications had been tried and doctors had started to question her mother’s parenting skills. Elizabeth’s parents had gone beyond frustration and fear for their child, they were at the point of desperation.

This is a common story in Dr Ford’s practice. It is also one of the many success stories he has to share. After seeing Dr Ford, a positive IgG-gliadin antibody test and being put on a gluten free diet, Elizabeth improved within a few days. Within weeks she made a remarkable recovery and was in essence cured. Gluten was no longer a choice for her and accidental intake still causes her a reoccurrence of symptoms. Adhering to a gluten free diet has enabled Elizabeth to grow into the healthy, happy and successful young woman that she is today.

Common stories such as this, along with the increasing research and evidence of gluten based harm, should be enough to spur the medical profession into action in an effort to save the current generation of children from the long term health, social and financial consequences of what is an easily diagnosed and treatable condition.

The shocking truth is that this terrible scourge of gluten is being ignored by most medical practitioners. Even worse, the blood tests that can diagnose it are being abandoned by many medical laboratories. For instance, Medlab Diagnostics in Auckland no longer offers gliadin antibody tests.

The medical professions reluctance to act on the gluten problem is costing New Zealand billions of dollars each year with long term and far reaching consequences. From a dollars and cents point of view it makes no economic sense. From a patient care point of view it is bordering on negligence.
Source: Scoop Independent News, New Zealand, Thursday, 19 June 2008, 9:49 am

You can find this news release at http://www.scoop.co.nz/stories/GE0806/S00059.htm

———————————–
Author Information: John Libonati, Philadelphia, PA
Publisher, Glutenfreeworks.com.
Editor & Publisher, Recognizing Celiac Disease.
John can be reached by e-mail here.

About John Libonati

Avatar photo
Author Information: John Libonati, SW Florida Publisher, Glutenfreeworks.com & The Gluten Free Works Treatment Guide.

5 comments

  1. The information that has been provided at this site is soooo helpful. I appreciate your tenacity and work in getting the news out.

  2. Eliminate gluten: nope the doctors and big pharmaceuticals can’t make any money with that simple solution.

  3. Perrin Ehlinger

    I’m fairly convinced that the gliadin antibody tests are essentially worthless, and a much more accurate test would be serum zonulin or to find a way to test directly for gliadin fragments in blood or in an adipose tissue biopsy. Excepting Type 1 Diabetics (CD8-TCells), and Celiac’s, most people don’t develop an immune response directly to gliadin, but to its amyloid resultants, which has proven true in studies of IgA Nephropathy, and looks fairly accurate for most other amyloid diseases suspected of gliadin involvement. The first treatment for any illness related to amyloid sourced inflammation should be a gluten free diet.

    • Avatar photo

      Native gliadin can, and does, penetrate the intestinal lining by its own mechanism. Once in the blood, it elicits an immune reaction leading to the development of anti-gliadin antibodies. It should be included in any test for celiac disease or gluten sensitivity. Others, like anti-deamidated gliadin and anti-tissue transglutaminase should also be employed, but discounting anti-gliadin is a mistake. Once the gluten free diet is adopted, levels of gluten-related antibodies drop, and blood levels may not rise again after reintroduction, so testing should be performed first.

Leave a Reply

Your email address will not be published. Required fields are marked *

*

x

Check Also

My Food Revolution: How I Became Gluten-free & Dairy-free

Every morning my freshman year in high school, I felt sick. I would miss a ...

Were You Diagnosed with Gluten Sensitivity or Celiac Disease by a Doctor or Did You Figure It Out on Your Own?

It is well documented that only a small minority of those with celiac disease are ...

Who Needs a Gluten Test? Video by “Gluten Syndrome” Expert Dr. Rodney Ford Explains

Dr. Rodney Ford, pediatrician and author of The Gluten Syndrome, provides us with an excellent ...