What Is Easy Bruising? Ecchymosis, or easy bruising, is a feature of impaired secondary hemostasis (blood clotting) characterized by subcutaneous bleeding (under the skin) in response to light trauma. Q: What causes easy bruising? A: Easy bruising is the direct ...
Read More »Atherosclerosis
What Is Atherosclerosis? Atherosclerosis is a disease of arteries involving the buildup of fatty material called plaque along the walls of medium and large arteries characterized by patchy subintimal thickening, hardening, and loss of elasticity of blood vessels. The intima is the ...
Read More »Erythroblastopenia, Transient
What Is Transient Erythroblastopenia? Transient erythroblastopenia is a rare disorder of red blood cell formation characterized by brief, reversible disappearance of erythroblasts (red blood cell precursors) in the bone marrow of children. Q: What do the red blood cells look ...
Read More »Neutropenia
What Is Neutropenia? Neutropenia is a blood disorder characterized by presence of an abnormally low number of neutrophils. Neutrophils are white blood cells (leukocytes) that serves as the primary defense against infections by destroying bacteria in the blood. Specfically, neutrophils are ...
Read More »Immune Thrombocytopenic Purpura
What Is Immune Thrombocytopenic Purpura? Immune thrombocytopenia purpura (ITP), formerly called idiopathic, is an immune mediated bleeding disorder characterized by destruction of circulating platelets (thrombocytes) by autoantibodies in the presence of normal bone marrow and without other conditions that cause ...
Read More »Hypoprothrombinemia (Low Prothrombin Level)
What Is Hypoprothrombinemia? Hypoprothrombinemia is a deficiency of prothrombin (clotting factor II) in the blood that is characterized by impaired hemostasis in response to trauma or a laceration. Q: What is hemostasis and how is it altered by a deficiency of prothrombin? A: Hemostasis ...
Read More »Hemochromatosis (Iron Overload Disease)
What Is Hemochromatosis? Hemochromatosis, also called iron overload liver disease, is a common inherited disease in the Caucasian population that is characterized by increased iron deposition within the tissues (overload) associated with injury to them. Hemochromatosis is an autosomal recessive disease, meaning ...
Read More »Macrolipasemia
What Is Macrolipasemia? Macrolipasemia is a rare enzyme disorder characterized by altered molecules of lipase, a pancreatic enzyme needed to digest fats, that are abnormally bound with serum antibody proteins. These antibodies are commonly immunoglobulin G (IgG) and/or less likely immunoglobulin A ...
Read More »Macrocytosis
What Is Macrocytosis? Macrocytosis is a blood cell disorder characterized by altered blood cell formation that results in abnormally large erythrocytes (red blood cells) circulating in the bloodstream. The mean corpuscular volume (MCV), which is a measure of the size of ...
Read More »Macroamylasemia
What Is Macroamylasemia? Macroamylasemia is an acquired enzyme disorder that causes elevated levels of the enzyme amylase (hyperamylasaemia) in the bloodstream. It is characterized by altered amylase molecules that have become abnormally bound with plasma proteins in the bloodstream, commonly ...
Read More »Hypophosphatemia (Low Phosphate Blood Level)
What Is Hypophosphatemia? Hypophosphatemia means the level of phosphates in the bloodstream is too low to meet metabolic needs of the body for this mineral. Q: How important is phosphorus in metabolism? A: Phosphorus is crucial to life, being present ...
Read More »Hypoglycemia (Low Blood Sugar)
What Is Hypoglycemia? Hypoglycemia means the level of glucose within cells is too low to meet metabolic needs of the body for this essential sugar. Q: What are the metabolic needs for glucose? A: Glucose is the most important simple ...
Read More »Hypocalcemia (Low Blood Calcium)
What Is Hypocalcemia? Hypocalcemia, or low plasma calcium, means the level of calcium in blood is too low to meet metabolic needs of the body for calcium. Low blood calcium is characterized by bone and tooth demineralization (loss of calcium ...
Read More »Liver Enzymes, Elevated (Hypertransaminasemia)
What Are Elevated Liver Enzymes? Hypertransaminasemia is a chronic condition of elevated blood liver transaminase enzymes, commonly called “liver enzymes,” that signifies hepatocellular (liver) injury. Q: What are serum transaminases? A: Transaminases are the liver enzymes ALT and AST. ALT is the ...
Read More »Hyperprolactinemia (Excess Prolactin Hormone)
What Is Hyperprolactinemia? Hyperprolactinemia is an excess secretion of prolactin hormone causing an elevated blood level that is characterized by its effects on reproduction: in females causing amenorrhea and in males causing reduced sexual potency. Q: What is prolactin? A: ...
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