Lymphocyte Disorders

What Is Intraepithelial Lymphocytosis In Normal Small Bowel Samples? Intraepithelial lymphocytosis is characterized by an abnormal increase in the numbers of intraepithelial lymphocytes (IELs) that are present in the small intestinal mucosa. Q: What are intraepithelial lymphocytes? A: Intraepithelial lymphocytes are ...

What Is Cancer Predisposition In Children? Cancer predisposition in children signifies a higher than normal risk of developing cancer. Cancer is the uncontrolled division of abnormal cells in the body. Among the 12 major types of childhood cancers, leukemias (blood ...

What Is Enteropathy-Associated T-Cell Lymphoma? Enteropathy associated T-cell lymphoma (EATL), although rare, is a tumor of intraepithelial lymphocytes. It is the most common primary gastrointestinal T-cell lymphoma and is characterized by its aggressive course and poor prognosis. Primary means this ...

What Are Extraintestinal Lymphomas? Extraintestinal lymphomas (non-Hodgkin’s) are malignancies that arise in peripheral lymphatic tissue outside the intestinal tract from B-cell and T-cell lymphocytes. Q: What is peripheral lymphatic tissue? A: Peripheral lymphatic tissue includes lymph vessels, lymph, lymph nodes, and ...

What Is Refractory Celiac Disease? Refractory celiac disease, formerly called refractory sprue, is a severe complication characterized by persistence of symptoms and intestinal inflammation despite gluten free diet after 12 months.1 Refractory celiac disease appears in two forms, ulcerative jejunitis (RCD ...

What Is B-Cell Non-Hodgkin’s Lymphoma? Bcell non-Hodgkin’s lymphoma is a malignant, monoclonal (arising from a single cell) proliferation of lymphocytes that is preceded by lymphadenopathy and characterized by varying, less predictable spread than Hodgkin’s disease. Lymphadenopathy is enlargement of lymph ...