What Is Common Variable Immunodeficiency? Common variable immunodeficiency (CVID) is a primary antibody deficiency disease characterized by the onset of recurrent bacterial infections resulting from markedly decreased immunoglobulin antibody production and antibody levels. Q: What causes common variable immunodeficiency? A: Common variable ...
Read More »Primary Hyperparathyroidism
What Is Primary Hyperparathyroidism? Primary hyperparathyroidism is a parathyroid disorder characterized by excessive secretion of parathyroid hormone by one or more parathyroid glands for more than 6 months. In primary hyperparathyroidism, blood calcium levels are high while phosphorus levels are ...
Read More »Bleeding, Occult Gastrointestinal
What Is Occult Gastrointestinal Bleeding? Occult gastrointestinal bleeding is characterized by unseen or minute quantities of blood in stool. The origin of bleeding is from mucosa that lines the inside of the digestive tract at a site that must be ...
Read More »Diarrhea, Acute
What Is Acute Diarrhea? Acute diarrhea is a small intestinal motility disorder characterized by excessively rapid movement of intestinal contents through the small intestine with excessive loss of fluid and electrolytes that leads rapidly to a life threatening hypokalemia (low ...
Read More »Cancer Of The Esophagus
What Is Cancer Of The Esophagus? Cancer of the esophagus is a malignancy arising in the stratified squamous cell lining of any part of the esophagus and having a poor prognosis. This tumor first invades the deeper layers of the ...
Read More »Cancer, Post-Cricoid
What Is Post-Cricoid Carcinoma? Post-cricoid carcinoma is a rare malignancy arising in the hypopharynx. Q: What is the hypopharynx? A: The hypopharynx is the lower portion of the pharynx that opens into the larynx. It is comprised of the postcricoid ...
Read More »Laryngospasm
What Is Laryngospasm? Laryngospasm is an acute disorder of the larynx that is characterized by life-threatening spasms of the muscles of the larynx located in the throat. Laryngospasm is a rare feature of hypocalcemia (low blood calcium level) characterized by ...
Read More »Oral Mucosal Lesions, Chronic (Mouth Soreness)
What Are Chronic Oral Mucosal Lesions? Chronic lesions of the oral mucosa are disorders of the mouth that are characterized by soreness and sores of the soft mucosal lining of the mouth. What Are Chronic Oral Mucosal Lesions In Celiac ...
Read More »Vitality, Loss of
What Is Loss of Vitality? Loss of vitality is a state of diminished power to live or go on living, interfering with normal functioning and survival. As weakness and fatigue worsen, the affected person increasingly loses interest in surroundings, activites, and ...
Read More »Nosebleeds, Unexplained (Epistaxis)
What Is Epistaxis? Epistaxis, or nosebleed, is a feature of secondary hemostasis (blood clotting) characterized by fragility of a plexus of blood vessels in the antero-inferior septum (just inside nostril) and/or abnormal blood coagulation. What Is Epistaxis In Celiac Disease ...
Read More »Bruising, Easy (Ecchymosis)
What Is Easy Bruising? Ecchymosis, or easy bruising, is a feature of impaired secondary hemostasis (blood clotting) characterized by subcutaneous bleeding (under the skin) in response to light trauma. Q: What causes easy bruising? A: Easy bruising is the direct ...
Read More »Atherosclerosis
What Is Atherosclerosis? Atherosclerosis is a disease of arteries involving the buildup of fatty material called plaque along the walls of medium and large arteries characterized by patchy subintimal thickening, hardening, and loss of elasticity of blood vessels. The intima is the ...
Read More »Hypocalcemia (Low Blood Calcium)
What Is Hypocalcemia? Hypocalcemia, or low plasma calcium, means the level of calcium in blood is too low to meet metabolic needs of the body for calcium. Low blood calcium is characterized by bone and tooth demineralization (loss of calcium ...
Read More »Coagulation Factors, Low
What Are Low Coagulation Factors? Coagulation factors II, VII, IX, X found in blood are essential for normal blood clotting. Low coagulation factors on blood assay indicate an altered secondary coagulation disorder that is characterized by impaired clot formation. Each coagulation factor ...
Read More »Vitamin K Deficiency
What Is Vitamin K? Vitamin K is a family of fat-soluble vitamins, called K vitamers, that exists in three forms: K1 is a natural form found in plants (phylloquinone); K2, found in some animal foods, is synthesized in the intestine ...
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