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System – Integumentary (body surfaces)

This category comprises disorders of the integumentary system that cause damage to skin, nails and hair and/or impaired function.

Seborrhea Dermatitis

What Is Seborrhea Dermatitis? Seborrhea dermatitis is a recurring inflammatory disorder of sebaceous glands characterized by scaly patches of skin, often with bumps. Seborrhea dermatitis results from the body’s inflammatory reaction to invasion by pityrosporum yeast that naturally inhabits the ...

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Scleroderma (Systemic Sclerosis)

What Is Scleroderma? Scleroderma is a chronic skin manifestation of progressive systemic sclerosis characterized by generalized thickened, edematous skin firmly bound to subcutaneous tissue which causes limited movement. Systemic sclerosis a connective tissue disease that involves destructive changes in the ...

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Prurigo Nodularis (Hyde’s Prurigo)

What Is Prurigo Nodularis (Hyde’s Prurigo)? Prurigo nodularis is a chronic dermatitis characterized by hard, dry, deep seated, intensely itchy papules (small bumps like pimples) and/or nodules (large bumps) that erupt most commonly on the arms, legs, and back. Papules ...

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Dermatitis Herpetiformis In Childhood

What Is Dermatitis Herpetiformis In Childhood? Dermatitis herpetiformis in childhood is an inflammatory skin manifestation of celiac disease in which immunoglobulin A (IgA) autoantibodies target components of the skin, leading to blister formation caused by ingestion of gluten in the diet.   Dermatitis ...

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Itchy (Pruritic) Skin  

What Is Pruritic Skin? Pruritic skin is a symptom of a primary disease that may involve only the skin or a systemic disorder with other features and is characterized by chronic itching. Q: What part of skin is affected by ...

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Pityriasis Rubra Pilaris

What Is Pityriasis Rubra Pilaris? Pityriasis rubra pilaris (PRP) is a chronic generalized exfoliative dermatitis (sloughing skin) characterized by erythema (redness), scaling, dilated plugged hair follicles, and keratoderma (thickened skin) of the hands and feet that is often associated with ...

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Melanoma

What Is Melanoma? Melanoma is a cutaneous malignancy with rapid invasion and metastasis to other parts of the body. Melanoma is characterized by growth from melanocytes appearing as a new mole or enlarging from an exisiting mole, changing shape, size ...

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Ichthyosis, Acquired  

What Is Acquired Ichthyosis? Acquired ichthyosis is an uncommon, nonhereditary cutaneous disorder characterized by dry, rough skin with prominent symmetrical scaling that involves significant portions of the body. Most microscopic studies of acquired ichthyosis exhibit hyperkeratosis (thickened skin) with a ...

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Hangnail

What Is Hangnail? Hangnail is a broken strip of epidermis (piece of skin) at root or lateral (side) edge of fingernail or toenail that causes sharp pain. A hangnail develops because the skin around the nail is unhealthy due to ...

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Follicular Hyperkeratosis (goose flesh or corkscrew hair)

What Is Follicular Hyperkeratosis? Follicular hyperkeratosis is an abnormal skin condition characterized by disordered overgrowth of the horny layer of the epidermis with horny plugs filling the openings of hair follicles. The plugs look like bumps in hair follicles. Follicular ...

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Erythema Nodosum 

What Is Erythema Nodosum? Erythema nodosum is an inflammatory disorder involving the deep dermis layer of skin and subcutaneous fat septa that underlies the skin. It is characterized by eruptions of recurrent or persistent multiple painful, red nodules under the skin that ...

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Erythema Elevatum Diutinum (EED)

What Is Erythema Elevatum Diutinum? Erythema elevatum diutinum is a rare leucocytoclastic vasculitis thought to be caused by an immune response that is characterized by inflammation, a rash, and scarring of small blood vessels of the skin. A characteristic poorly defined ...

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Edema

What Is Edema? Edema is an abnormal swollen condition of the skin characterized by excess extracellular fluid volume, meaning there is an increase of the fluid that normally surrounds cells. Edema may be hardly noticeable or it can become extensive. ...

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Cutis Laxa, Acquired

What Is Acquired Cutis Laxa? Acquired cutis laxa is an uncommon skin disorder characterized by abnormal reduction and degeneration of elastic fibers of the skin that can appear simply as thick, saggy skin with loose folds to severe involvement showing ...

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Cutaneous Vasculitis 

What Is Cutaneous Vasculitis? Cutaneous vasculitis is a vascular disease of small blood vessels serving the skin that is characterized by segmental (spotty) inflammation of affected vessel walls resulting in their necrosis (destruction). Scarring is seen in the affected skin ...

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