What Is Cutaneous Vasculitis? Cutaneous vasculitis is a vascular disease of small blood vessels serving the skin that is characterized by segmental (spotty) inflammation of affected vessel walls resulting in their necrosis (destruction). Scarring is seen in the affected skin ...
Read More »Hair, Fine With Rough Texture
What Is Fine Hair With Rough Texture? Fine hair (lower diameter across the width) with rough texture is an abnormal hair shaft feature altered from the normal diameter and smooth quality of hair. Q: What is the normal diameter and smooth quality of ...
Read More »IgA Deficiency
What Is IgA Deficiency? IgA deficiency (IgAD) is an immunodeficiency disease characterized by lack of immunoglobulin A type antibody production, called IgA antibody, with no detectable levels in blood or secretions. Q: What is an IgA antibody? A: IgA is ...
Read More »Common Variable Immunodeficiency
What Is Common Variable Immunodeficiency? Common variable immunodeficiency (CVID) is a primary antibody deficiency disease characterized by the onset of recurrent bacterial infections resulting from markedly decreased immunoglobulin antibody production and antibody levels. Q: What causes common variable immunodeficiency? A: Common variable ...
Read More »Autoimmune Disorders In Dermatitis Herpetiformis
What Are Autoimmune Disorders? Autoimmune disorders refer to those conditions that involve an abnormal attack on the body’s own tissues perpetuated by the production of autoantibodies directed against self. Q: What happens when autoantibodies attack the body’s own tissues? A: ...
Read More »Allergic Rhinitis
What Is Allergic Rhinitis? Allergic rhinitis is an immune disorder characterized by inflammation of the nasal mucosa by an IgE antibody reaction to an allergen. An allergen is something that triggers an allergic immune response. Q: What is the immune ...
Read More »Primary Hyperparathyroidism
What Is Primary Hyperparathyroidism? Primary hyperparathyroidism is a parathyroid disorder characterized by excessive secretion of parathyroid hormone by one or more parathyroid glands for more than 6 months. In primary hyperparathyroidism, blood calcium levels are high while phosphorus levels are ...
Read More »Pancreatic Insufficiency
What Is Pancreatic Insufficiency? Pancreatic insufficiency is a disorder characterized by insufficient exocrine production of pancreatic enzymes for normal digestion of fats, proteins, and carbohydrates that results in maldigestion of these foodstuffs. Pancreatic insufficiency also causes malabsorption of the fat-soluble ...
Read More »Gastrointestinal Complications Of Type I Diabetes Mellitus
What Are Gastro-Intestinal Complications Of Type 1 Diabetes? Gastrointestinal complications of type I diabetes mellitus are functional or organic changes that result from diabetes affecting every organ of the gastrointestinal tract. Q: How do gastrointestinal tract complications affect diabetes? A: Impaired ...
Read More »Diabetic Instability
What Is Diabetic Instability? Diabetic instability, also called brittle diabetes, is poor control of blood sugar characterized by frequent rise (hyperglycemia) and fall (hypoglycemia). These fluctuations can be life-threatening and cause unnecessary complications. Q: What are complications in diabetes? A: Complications ...
Read More »Diabetes Mellitus, Type I
What Is Type I Diabetes Mellitus? Type 1 diabetes mellitus (T1DM), also termed type 1A, is an inherited autoimmune disorder in which anti-islet autoantibodies destroy the islet cells of the pancreas that secrete insulin hormone. Type 1 diabetes mellitus was formerly ...
Read More »Liver or Hepatic Granulomatous Disease
What Is Hepatic Granulomatous Disease? Hepatic granulomatous disease is an infiltrative chronic liver disorder characterized by growth of small granulomas. Rather than being a final diagnosis, the presence of hepatic granulomas entails the need for further investigations towards identifying the ...
Read More »Autoimmune Hepatitis
What Is Autoimmune Hepatitis? Autoimmune hepatitis is an autoimmune attack against liver cells that is characterized by inflammation and results in chronic liver disease which includes low blood albumin and cirrhosis. Autoimmune hepatitis is diagnosed by detection of autoantibodies ...
Read More »Milk Intolerance – Bovine Beta Casein Enteropathy
What Is Milk Intolerance (Bovine Beta Casein Enteropathy)? Bovine beta casein enteropathy is characterized by raised serum IgA antibodies to bovine beta casein found by blood testing and damage to mucosa of the jejunum found by biopsy. The jejunum is the second ...
Read More »Primary Sclerosing Cholangitis
What Is Primary Sclerosing Cholangitis? Primary sclerosing cholangitis (PSC) is an uncommon, slowly progressive bile duct disease that results in stagnation or build-up of bile in the liver, called cholestasis. Primary sclerosing cholangitis is characterized by sclerosis, or scarring inflammation ...
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