Autoimmune Disorders

This category comprises autoimmune disorders caused by an abnormal immune system attack against the body’s own tissue(s).

Almost half of autoimmune disorders occur with other diseases. Some are organ specific like autoimmune thyroid disease which attacks the thyroid gland, whereas others affect multiple organs and/or are associated with systemic manifestations, such as systemic lupus erythematosus.

Diabetes Mellitus, Type I

What Is Type I Diabetes Mellitus? Type 1 diabetes mellitus (T1DM), also termed type 1A, is an inherited autoimmune disorder in which anti-islet autoantibodies destroy the islet cells of the pancreas that secrete insulin hormone. Type 1 diabetes mellitus was formerly ...

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Gastrointestinal Complications Of Type I Diabetes Mellitus

gastrointestinal complications in diabetes symptom in gluten and celiac disease

What Are Gastro-Intestinal Complications Of Type 1 Diabetes? Gastrointestinal complications of type I diabetes mellitus are functional or organic changes that result from diabetes affecting every organ of the gastrointestinal tract. Q: How do gastrointestinal tract complications affect diabetes? A: Impaired ...

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Hair, Fine With Rough Texture

What Is Fine Hair With Rough Texture? Fine hair (lower diameter across the width) with rough texture is an abnormal hair shaft feature altered from the normal diameter and smooth quality of hair. Q: What is the normal diameter and smooth quality of ...

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Hashimoto’s Disease (Autoimmune Thyroiditis Causing Hypothyroidism)

What Is Autoimmune Thyroiditis (Hypothyroidism)? Autoimmune thyroiditis, also called Hashimoto’s thyroiditis or Hashimoto’s Disease, is an autoimmune destruction of thyroid tissue characterized by insufficient thyroid hormone circulating in the body that causes formation of a goiter (enlarged thyroid gland) and ...

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IgA Nephropathy

What Is IgA Nephropathy? IgA nephropathy, also called Berger’s disease, is a primary renal disease that results when immunoglobulin A (IgA) forms deposits in the glomeruli, where it creates inflammation. IgA nephropathy is characterized by recurrent hematuria (blood in urine), mild proteinuria ...

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Juvenile Autoimmune Thyroid Disease

What Is Juvenile Autoimmune Thyroid Disease? Juvenile autoimmune thyroid disease is an autoimmune disorder occurring in childhood that targets and damages the thyroid gland, often causing goiter. It is characterized by abnormal circulating thyroid hormone levels in the bloodstream. Recent evidence ...

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Juvenile Diabetes (Type 1 Diabetes Mellitus)

What Is Juvenile Type 1 Diabetes Mellitus? Juvenile diabetes is type I diabetes mellitus that begins in childhood or before the age of 25 years. It is an inherited inflammatory autoimmune disease of the pancreas in which anti-islet autoantibodies destroy the ...

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Polymyositis

What Is Polymyositis? Polymyositis is a body-wide connective tissue disease resulting from autoimmune attack of skeletal muscles that is characterized by inflammatory and degeneratory changes. The course is unpredictable being marked by spontaneous flare-ups and remissions. Polymyositis can begin slowly or abruptly according ...

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Primary Sclerosing Cholangitis 

What Is Primary Sclerosing Cholangitis? Primary sclerosing cholangitis (PSC) is an uncommon, slowly progressive bile duct disease that results in stagnation or build-up of bile in the liver, called cholestasis. Primary sclerosing cholangitis is characterized by sclerosis, or scarring inflammation ...

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Psoriasis

 What Is Psoriasis? Psoriasis is a chronic, autommune relapsing skin disorder characterized by scaling, erythema (redness), and less commonly, pustulation.1  The body surface area affected and the degree to which psoriasis is a problem varies considerably among patients and over time.2 Often ...

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Psoriatic Arthritis

What Is Psoriatic Arthritis? Psoriatic arthritis is a joint manifestation of psoriasis, a systemic autoimmune disease, characterized by asymmetric involvement in one or more joints, especially affecting the distal phalangeal joints of fingers and toes (joints nearest nails). In some ...

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Scleroderma (Systemic Sclerosis)

What Is Scleroderma? Scleroderma is a chronic skin manifestation of progressive systemic sclerosis characterized by generalized thickened, edematous skin firmly bound to subcutaneous tissue which causes limited movement. Systemic sclerosis a connective tissue disease that involves destructive changes in the ...

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Sjögren’s Syndrome 

What Is Sjögren’s Syndrome? Sjögren’s syndrome is a systemic inflammatory autoimmune disease with a chronic, progressive course that primarily attacks the lacrimal glands of the eye and the salivary glands of the mouth, which are exocrine glands. Exocrine glands secrete the substances they ...

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Systemic Lupus Erythematosus 

What Is Systemic Lupus Erythematosus? Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease that is characterized by involvement of multiple organs due to the production of antibodies to components of the cell nucleus.1 SLE has an unpredictable course of acute ...

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Vitiligo

What Is Vitiligo? Vitiligo is a pigmentation disorder of the skin characterized by permanent loss of melanocytes in defined areas and, in some patients, antibodies to melanin. Vitiligo has significant psychological impact if occurring before adulthood.1 Q: What are melanocytes? A: ...

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