What Is IgA Deficiency? IgA deficiency (IgAD) is an immunodeficiency disease characterized by lack of immunoglobulin A type antibody production, called IgA antibody, with no detectable levels in blood or secretions. Q: What is an IgA antibody? A: IgA is ...
Read More »Common Variable Immunodeficiency
What Is Common Variable Immunodeficiency? Common variable immunodeficiency (CVID) is a primary antibody deficiency disease characterized by the onset of recurrent bacterial infections resulting from markedly decreased immunoglobulin antibody production and antibody levels. Q: What causes common variable immunodeficiency? A: Common variable ...
Read More »Autoimmune Disorders In Dermatitis Herpetiformis
What Are Autoimmune Disorders? Autoimmune disorders refer to those conditions that involve an abnormal attack on the body’s own tissues perpetuated by the production of autoantibodies directed against self. Q: What happens when autoantibodies attack the body’s own tissues? A: ...
Read More »Allergic Rhinitis
What Is Allergic Rhinitis? Allergic rhinitis is an immune disorder characterized by inflammation of the nasal mucosa by an IgE antibody reaction to an allergen. An allergen is something that triggers an allergic immune response. Q: What is the immune ...
Read More »Diabetes Mellitus, Type I
What Is Type I Diabetes Mellitus? Type 1 diabetes mellitus (T1DM), also termed type 1A, is an inherited autoimmune disorder in which anti-islet autoantibodies destroy the islet cells of the pancreas that secrete insulin hormone. Type 1 diabetes mellitus was formerly ...
Read More »Milk Intolerance – Bovine Beta Casein Enteropathy
What Is Milk Intolerance (Bovine Beta Casein Enteropathy)? Bovine beta casein enteropathy is characterized by raised serum IgA antibodies to bovine beta casein found by blood testing and damage to mucosa of the jejunum found by biopsy. The jejunum is the second ...
Read More »Primary Sclerosing Cholangitis
What Is Primary Sclerosing Cholangitis? Primary sclerosing cholangitis (PSC) is an uncommon, slowly progressive bile duct disease that results in stagnation or build-up of bile in the liver, called cholestasis. Primary sclerosing cholangitis is characterized by sclerosis, or scarring inflammation ...
Read More »Erythroblastopenia, Transient
What Is Transient Erythroblastopenia? Transient erythroblastopenia is a rare disorder of red blood cell formation characterized by brief, reversible disappearance of erythroblasts (red blood cell precursors) in the bone marrow of children. Q: What do the red blood cells look ...
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