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System – Immune

This category comprises disorders of the immune system that cause damage to tissues and/or impairment of its protective function against invading organisms. The immune system includes proteins such as interferons, chemicals such as histamine, white blood cells including phagocytes and leukocytes, and immunoglobulins (antibodies).

Food Allergy – IgE and Non IgE

What Is Food Allergy? Food allergy is an abnormal immune response to food proteins that may damage the small intestinal  lining and produce malabsorption of food. The reaction is usually delayed which makes it difficult to identify the offending food that ...

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IgA Deficiency

What Is IgA Deficiency? IgA deficiency (IgAD) is an immunodeficiency disease characterized by lack of immunoglobulin A type antibody production, called IgA antibody, with no detectable levels in blood or secretions. Q: What is an IgA antibody? A: IgA is ...

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Iron Deficiency

What Is Iron? Iron is an essential mineral that is required for normal body function. Almost two-thirds of iron in the body is found in hemoglobin, the protein in red blood cells that carries oxygen to tissues. Smaller amounts of ...

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Milk Intolerance – Bovine Beta Casein Enteropathy

What Is Milk Intolerance (Bovine Beta Casein Enteropathy)? Bovine beta casein enteropathy is characterized by raised serum IgA antibodies to bovine beta casein found by blood testing and damage to mucosa of the jejunum found by biopsy. The jejunum is the second ...

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Primary Sclerosing Cholangitis 

What Is Primary Sclerosing Cholangitis? Primary sclerosing cholangitis (PSC) is an uncommon, slowly progressive bile duct disease that results in stagnation or build-up of bile in the liver, called cholestasis. Primary sclerosing cholangitis is characterized by sclerosis, or scarring inflammation ...

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Sarcoidosis

What Is Sarcoidosis? Sarcoidosis is a multisystem granulomatous disease characterized by hard granulomas and inflammation of the alveoli in lungs that occurrs in 80% of patients. Alveoli are the tiny one cell thick round structures that are clustered at the ...

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Sjögren’s Syndrome 

What Is Sjögren’s Syndrome? Sjögren’s syndrome is a systemic inflammatory autoimmune disease with a chronic, progressive course that primarily attacks the lacrimal glands of the eye and the salivary glands of the mouth, which are exocrine glands. Exocrine glands secrete the substances they ...

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Systemic Lupus Erythematosus 

What Is Systemic Lupus Erythematosus? Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease that is characterized by involvement of multiple organs due to the production of antibodies to components of the cell nucleus.1 SLE has an unpredictable course of acute ...

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