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Antibody Disorders

This category comprises disorders that are caused by an immune mechanism producing antibodies.

Antibodies are specialized proteins of the immune system called immunoglobulins. Each antibody consists of 4 polypeptides, comprised of about 100 amino acids, forming a Y shaped molecule. The site on the antibody that binds with an antigen is at the tips of the Y. Each antibody is unique and defends the body against the one specific antigen it recognizes.
Antibodies that target the body’s own tissue are called autoantibodies. Auto means “self.”

Juvenile Autoimmune Thyroid Disease

What Is Juvenile Autoimmune Thyroid Disease? Juvenile autoimmune thyroid disease is an autoimmune disorder occurring in childhood that targets and damages the thyroid gland, often causing goiter. It is characterized by abnormal circulating thyroid hormone levels in the bloodstream. Recent evidence ...

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Milk Intolerance – Bovine Beta Casein Enteropathy

What Is Milk Intolerance (Bovine Beta Casein Enteropathy)? Bovine beta casein enteropathy is characterized by raised serum IgA antibodies to bovine beta casein found by blood testing and damage to mucosa of the jejunum found by biopsy. The jejunum is the second ...

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Sjögren’s Syndrome 

What Is Sjögren’s Syndrome? Sjögren’s syndrome is a systemic inflammatory autoimmune disease with a chronic, progressive course that primarily attacks the lacrimal glands of the eye and the salivary glands of the mouth, which are exocrine glands. Exocrine glands secrete the substances they ...

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Systemic Lupus Erythematosus 

What Is Systemic Lupus Erythematosus? Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease that is characterized by involvement of multiple organs due to the production of antibodies to components of the cell nucleus.1 SLE has an unpredictable course of acute ...

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Urticaria or Hives, Chronic

What Is Chronic Urticaria? Urticaria is an immune based skin disorder characterized by multiple eruptions of well-demarcated edematous, intensely pruritic (itchy) plaques that may be small or reach the diameter of many centimeters with surrounding erythema (redness) each lasting less ...

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