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Antibody Disorders

This category comprises disorders that are caused by an immune mechanism producing antibodies.

Antibodies are specialized proteins of the immune system called immunoglobulins. Each antibody consists of 4 polypeptides, comprised of about 100 amino acids, forming a Y shaped molecule. The site on the antibody that binds with an antigen is at the tips of the Y. Each antibody is unique and defends the body against the one specific antigen it recognizes.
Antibodies that target the body’s own tissue are called autoantibodies. Auto means “self.”

Common Variable Immunodeficiency 

What Is Common Variable Immunodeficiency? Common variable immunodeficiency (CVID) is a primary antibody deficiency disease characterized by the onset of recurrent bacterial infections resulting from markedly decreased immunoglobulin antibody production and antibody levels. Q: What causes common variable immunodeficiency? A: Common variable ...

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Autoimmune Disorders In Dermatitis Herpetiformis

What Are Autoimmune Disorders? Autoimmune disorders refer to those conditions that involve an abnormal attack on the body’s own tissues perpetuated by the production of autoantibodies directed against self. Q: What happens when autoantibodies attack the body’s own tissues? A: ...

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Allergic Rhinitis

What Is Allergic Rhinitis? Allergic rhinitis is an immune disorder characterized by inflammation of the nasal mucosa by an IgE antibody reaction to an allergen. An allergen is something that triggers an allergic immune response. Q: What is the immune ...

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Diabetes Mellitus, Type I

What Is Type I Diabetes Mellitus? Type 1 diabetes mellitus (T1DM), also termed type 1A, is an inherited autoimmune disorder in which anti-islet autoantibodies destroy the islet cells of the pancreas that secrete insulin hormone. Type 1 diabetes mellitus was formerly ...

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Milk Intolerance – Bovine Beta Casein Enteropathy

What Is Milk Intolerance (Bovine Beta Casein Enteropathy)? Bovine beta casein enteropathy is characterized by raised serum IgA antibodies to bovine beta casein found by blood testing and damage to mucosa of the jejunum found by biopsy. The jejunum is the second ...

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