Antibodies, Anti-tissue Transglutaminase (tTG): definition Posted by: Cleo Libonati, RN, BSN in DICTIONARY 0 2,040 Views Auto-antibodies produced against the muscle enzyme, transglutaminase, by persons who have inherited the genes for celiac disease, an autotimmune disorder triggered by ingestion of gluten in the diet. Glossary. 2013-04-08 Cleo Libonati, RN, BSN