“Psoriasis: 7 New Genetic Clues”
Newly Discovered Genetic Variations May Make Psoriasis More Likely, Study Shows
By Miranda Hitti
WebMD Medical NewsReviewed by Louise Chang, MDApril 3, 2008 — Scientists have discovered seven genetic variations linked to psoriasis.
What Is Zincemia?Zincemia means the zinc level in blood plasma is too low to meet metabolic needs of the body for this mineral.
Q: How important is a normal blood level of zinc?
A: A low blood level of zinc is characterized by widespread alterations in energy metabolism, growth, hemoglobin, carbon dioxide transport, hormone activity, insulin storage, many enzyme activities, prostaglandin function, collagen production, male fertility, protein synthesis, and vitamin A metabolism.
Zinc is an essential trace mineral that is involved in numerous aspects of cellular metabolism, being essential for activation of almost 200 enzymes that have vital roles in the body.
Q: What happens when enzymes do not get activated?
A: When enzymes do not get activated, they cannot perform their necessary functions which, in turn, damages health.
Zinc promotes healthy skin, hair, immunity, fertility, and growth.
A daily intake of zinc is required to maintain a steady state because the body has no specialized zinc storage system.1 Functions are more fully described below.
M acrolipasemia is a rare enzyme disorder characterized by altered molecules of lipase, a pancreatic enzyme needed to digest fats, that are abnormally bound with serum antibody proteins. These antibodies are commonly immunoglobulin G (IgG) and/or less likely immunoglobulin A (IgA).
Q: What happens when lipase is bound to immunoglobulins (IgA and/or IgG)?
A: The resulting molecule is too large to be filtered by the kidneys and excreted in the urine, consequently these abnormal molecules build up in the plasma causing sustained elevation of lipase levels called macrolipasemia.
Macrolipasemia occurs with or without macroamylasemia, which is the binding of immunoglobulin A and/or G to amylase, a pancreatic enzyme needed to digest starches.1
What Is A Fiery Red, Smooth, Burning Tongue?A fiery red, smooth, burning tongue is an alteration in tongue tissue that is characteristic of advanced niacin deficiency.1
Q: How does niacin deficiency cause the tongue to be red and sore?
A: Niacin is an essential B vitamin that is required for a healthy tongue and by all body cells as well. Deficiency first shows in tissues with rapid cellular turnover, such as mucosal cells of the tongue.
When absorbed from the small intestines, niacin (the form in food) becomes the active form niacinamide. Niacinamide is converted by the body into co-enzymes which are present in all cells. These enzymes function in oxidation-reduction reactions essential for release of energy from carbohydrates, fats, and proteins and are needed as components for more than 200 enzymes involved in metabolism.
In addition to producing energy, niacinamide is essential for healthy skin and the mucosal lining of the digestive tract, normal functioning of the brain and nervous system, and production of steroid hormones from adrenal glands and hormones from sex glands.
A chronic relapsing dermatosis characterized by scaling, erythema (redness), and less commonly pustulation that is an associated disorder of celiac disease involving deficiencies of omega-3 fatty acids, vitamin D, and zinc – features of malnutrition.…
A joint manifestation of psoriasis, a systemic autoimmune disease, characterized by asymmetric involvement in one or more joints, especially affecting the distal phalangeal joints of fingers and toes at tips.