A chronic inflammatory skin disease characterized by intensely itchy, red skin eruptions appearing on the extensor surfaces of the elbows, knees, back, buttocks, or scalp associated with sensitivity of the small intestsine to gluten in…
[dropcap]C opper is an essential trace element that is required for a number of enzymes which are necessary for normal metabolic function.
In the body almost all the copper is present as a component of copper proteins which are produced and controlled by the liver.
Q: How does the liver control copper?
A: The liver maintains proper copper balance by binding free copper to proteins and by excreting excess copper as part of bile that is then emptied into the intestinal tract and excreted in stool.
Metabolic balance studies have demonstrated that daily copper losses are approximately 1.3 mg/day.1
Among its specific functions listed below, copper is essential for energy production, blood and nerve functions, blood components, immunity, and collagen tissue. The copper enzyme, lysyl oxidase, is involved in the cross-linking of collagen in forming the framework for depositing calcium and other minerals to build and repair bone.
Animal studies suggest that adequate copper levels during pregnancy are critical to development of higher brain function in the offspring.2
What Is Copper Deficiency In Celiac Disease and/or Gluten Sensitivity?
Sources:
Williams DM. Copper deficiency in humans. Semin Hematol. 1983 Apr; 20(2):118-28. [↩]
Fisgin T, Yarali N, Duru F, Usta B, Kara A. Hematologic manifestation of childhood celiac disease. Acta Haematol. 2004;111(4):211-4. [↩]
A joint manifestation of psoriasis, a systemic autoimmune disease, characterized by asymmetric involvement in one or more joints, especially affecting the distal phalangeal joints of fingers and toes at tips.
Low coagulation factors, PT, PTT and Factors II, IX, X found in blood analysis is an abnormal level indicating an altered secondary coagulation disorder that is characterized by impaired formation of clot.
An immunologically mediated systemic disease of the connective tissue characterized by inflammatory and degenerative changes in the muscles and in the skin.
[dropcap]C hromium is a mineral that the body absolutely requires in trace amounts for normal metabolism, meaning the physical and chemical processes by which energy is produced and used.
Chromium is especially involved in the use of glucose sugar and lipids such as cholesterol and the effectiveness of insulin hormone.
Q: How is chromium involved in the use of glucose?
A: Very small amounts of chromium are required to enable insulin to move glucose from the bloodstream into cells for use as energy.
Insulin is a hormone that controls the use and storage of glucose in two ways: 1) lowers a rise of glucose in blood after meals by moving it out of the bloodstream into body cells, especially muscle cells and 2) limits the release of glucose from the liver between meals. Insulin is produced by beta cells on the surface of the pancreas.
To date, the molecular mechanism by which chromium affects glucose and lipid metabolism is still unclear.1
What Is Chromium Deficiency In Celiac Disease and/or Gluten Sensitivity?
Sources:
Lewicki S, Zdanowski R, Krzyżowska M, Lewicka A, Dębski B, Niemcewicz M, Goniewicz M. The role of Chromium III in the organism and its possible use in diabetes and obesity treatment. Ann Agric Environ Med. 2014 Jun 10;21(2):331-335. [↩]