According to the National Digestive Diseases Information Clearing House, a study published in the December 2008 issue of the Journal of Insurance Medicine reports that researchers from Columbia University and CIGNA HealthCare found that diagnosis of celiac disease substantially reduces subsequent health care costs.
The research group, led by Peter Green, M.D., a renowned authority in celiac disease from Columbia University, looked at medical records for 10.2 million CIGNA managed care members.
Contact: Sally Webster s.webster@qmul.ac.uk
44-207-882-5404
Queen Mary, University of London
Scientists who last year identified a new genetic risk factor for coeliac disease, have, following continued research, discovered an additional seven gene regions implicated in causing the condition. The team, lead by David van Heel, Professor of Gastrointestinal Genetics at Barts and The London School of Medicine and Dentistry, have further demonstrated that of the nine coeliac gene regions now know, four of these are also predisposing factors for type 1 diabetes. Their research sheds light not only on the nature of coeliac disease, but on the common origins of both diseases. It is published online today (2 March 2008) in Nature Genetics.
Dear Everyone: We wanted to share with you the avalanche of new mercury-autism studies published yesterday in the peer-reviewed literature. Yesterday, there were six studies published in one day that implicate a causal role for mercury exposure in autistic disorders.
(1) Sorting Out the Spinning of Autism – Heavy Metals – Mercury – & Incidence
“We analyzed the data reported in some articles that have been, or might be, taken to support the view of no-real-increase or no-environmental-connection. Overall, we have offered a critical view of some of the literature from the perspective of research scientists who have become interested in the topic within the past five years and sought to gauge the actual state of scientific knowledge regarding autism etiology… To summarize, of the 58 empirical reports on autism and heavy metal toxins, 43 suggest some link may be present, while 13 reports found no link. Even with the tendency for null results not to be reported,it cannot be said there is no evidence for a link between heavy metal toxins and autism: although the question may still be open-in sum, the evidence favors a link.“
ScienceDaily (July 22, 2010) — Walter and Eliza Hall Institute scientists have identified the three protein fragments that make gluten — the main protein in wheat, rye and barley — toxic to people with coeliac disease.
Professor Bob Anderson from the Walter and Eliza Hall Institute in Melbourne, Australia, has identified the three protein fragments that make gluten -- the main protein in wheat, rye and barley -- toxic to people with celiac disease. (Credit: Czesia Markiewicz, Walter and Eliza Hall Institute)
Their discovery opens the way for a new generation of diagnostics, treatments, prevention strategies and food tests for the millions of people worldwide with coeliac disease.
When people with coeliac disease eat products containing gluten their body’s immune response is switched on and the lining of the small intestine is damaged, hampering their ability to absorb nutrients. The disease is currently treated by permanently removing gluten from the patient’s diet.
Dr Bob Anderson, head of the Walter and Eliza Hall Institute’s coeliac disease research laboratory, said it had been 60 years since gluten was discovered to be the environmental cause of coeliac disease.
“In the years since, the holy grail in coeliac disease research has been to identify the toxic peptide components of gluten; and that’s what we’ve done,” Dr Anderson said.
The research, done in collaboration with Dr Jason Tye-Din, Dr James Dromey, Dr Stuart Mannering, Dr Jessica Stewart and Dr Tim Beissbarth from the institute as well as Professor Jamie Rossjohn at Monash University and Professor Jim McCluskey at the University of Melbourne, is published in the journalScience Translational Medicine.
Dr. Bob Anderson & John Libonati at an NFCA-sponsored event April 30, 2009 in Philadelphia, USA where Dr. Anderson described his research and vaccine.
The study was started by Professor Anderson nine years ago and has involved researchers in Australia and the UK as well as more than 200 coeliac disease patients.
The patients, recruited through the Coeliac Society of Victoria and the Coeliac Clinic at John Radcliffe Hospital, UK, ate bread, rye muffins or boiled barley. Six days later, blood samples were taken to measure the strength of the patients’ immune responses to 2700 different gluten fragments. The responses identified 90 fragments as causing some level of immune reaction, but three gluten fragments (peptides) were revealed as being particularly toxic.
“These three components account for the majority of the immune response to gluten that is observed in people with coeliac disease,” Dr Anderson said.
THURSDAY, July 24 (HealthDay News) — Researchers believe they have finally answered a basic question about the cause of celiac disease — where in the body does the wheat protein gluten enter one’s…
PRESS RELEASE Milestone Marks the First Time a European Patient with Active Celiac Disease has Enrolled in a Clinical Trial for an Investigational Medication from Alba Therapeutics Last update: 8:22 p.m. EST Nov. 11,…
Contact: Sally Webster s.webster@qmul.ac.uk 44-207-882-5404 Queen Mary, University of London Scientists who last year identified a new genetic risk factor for coeliac disease, have, following continued research, discovered an additional seven gene regions implicated in…
