{"id":816,"date":"2013-04-29T19:49:12","date_gmt":"2013-04-29T19:49:12","guid":{"rendered":"http:\/\/www.mynutriguide.com\/?p=816"},"modified":"2019-12-26T12:43:42","modified_gmt":"2019-12-26T17:43:42","slug":"infertility-2","status":"publish","type":"post","link":"https:\/\/glutenfreeworks.com\/health\/infertility-2\/","title":{"rendered":"Infertility In Males"},"content":{"rendered":"<h2><a href=\"https:\/\/glutenfreeworks.com\/health\/wp-content\/uploads\/sites\/10\/P6080044-False-colour_SEM_of_human_seminiferous_tubules-SPL.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-7019\" src=\"https:\/\/glutenfreeworks.com\/health\/wp-content\/uploads\/sites\/10\/P6080044-False-colour_SEM_of_human_seminiferous_tubules-SPL-300x229.jpg\" alt=\"P6080044-False-colour_SEM_of_human_seminiferous_tubules-SPL\" width=\"300\" height=\"229\" srcset=\"https:\/\/glutenfreeworks.com\/health\/wp-content\/uploads\/sites\/10\/P6080044-False-colour_SEM_of_human_seminiferous_tubules-SPL-300x229.jpg 300w, https:\/\/glutenfreeworks.com\/health\/wp-content\/uploads\/sites\/10\/P6080044-False-colour_SEM_of_human_seminiferous_tubules-SPL.jpg 350w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a>What Is Infertility in Males?<\/h2>\n<p style=\"text-align: justify\"><span class=\"dropcap\">I<\/span>nfertility in males is characterized by inability to either produce sperm or to produce viable sperm or mobile sperm resulting in prohibiting fertilization of the female ovum (egg).<\/p>\n<p style=\"text-align: justify\">To the left is a false-colour scanning electron micrograph of seminiferous tubules in the human testis (cross section), the site of production and maturation of sperm.<\/p>\n<p style=\"text-align: justify\">Round undifferentiated cells lining the tubule wall (brown, pink) become sperm by halving their chromosome number, and transforming in a process which takes about two months. During this time the cells move toward the centre of the tubule and develop tails (orange). Mature sperm migrate up the cavity of the tubule and are stored in the epididymis. 200-300 million sperm are released in an average ejaculation.<em> Courtesy of\u00a0<a title=\"Click here to view all the images by this contributor\" href=\"http:\/\/www.sciencephoto.com\/search?subtype=contributors&amp;searchstring=PMT&amp;media_type=images\">Professor P. Motta, Dept.of Anatomy, University of Rome Science Photo Library<\/a>.<\/em><\/p>\n<p style=\"text-align: justify\">Male androgen hormones control the development and maintenance of male sex organs and masculine secondary sex characteristics and are\u00a0required for health, especially bone health.<\/p>\n<p style=\"text-align: justify\">Testosterone is the major andogen hormone. While most of this steroid is produced by the testes, some is also produced by the adrenal glands.<\/p>\n<h2>What Is Infertility In Males In Celiac Disease and\/or Gluten Sensitivity?<\/h2>\n<p><!--more--><\/p>\n<ul class=\"cp_check red\">\n<li style=\"text-align: justify\">Infertility in males is a classic\u00a0reproductive symptom of celiac disease and may be a presenting feature of untreated celiac disease.<\/li>\n<li style=\"text-align: justify\">Gonadal dysfunction is believed due to reduced conversion of testosterone to dihydrotestosterone caused by low levels of 5 alpha-reductase in celiac disease, leading to derangement of the hypothalmic-pituitary axis.<\/li>\n<li style=\"text-align: justify\">Hyper-prolactinemia seen in 25% of celiac disease patients causes androgen deficiency and infertility.<a href=\"#footnote_1_816\" id=\"identifier_1_816\" class=\"footnote-link footnote-identifier-link\" title=\"Sher KS, Jayanthi V, Probert CS, Stewart CR, Mayberry JF. Infertility, obstetric and gynaecological problems in coeliac sprue. Digestive Diseases. May-Jun 1994;12(3):186-90.\">1<\/a>\u00a0\u00a0Zinc deficiency alters androgen production.<\/li>\n<li style=\"text-align: justify\">The detection of early biomarkers of andrological or endocrinological dysfunctions should trigger timely strategies for prevention and treatment. Hormone alterations are reversible upon the start of the gluten free diet, emphasizing the importance of early diagnosis; this should be performed in the case of clinical suspicion, e.g. unexplained hypoandrogenism.<\/li>\n<li style=\"text-align: justify\">Nutritionally, the folic acid deficiency of celiac disease can affect rapidly proliferating tissues such as the seminiferous epithelium. More attention should be paid to deficiencies of fat-soluble vitamins, such as A and D, observed in celiac disease. Vitamin A is important for Sertoli cell function as well as for early spermatogenetic phases. Vitamin E supports the correct differentiation and function of epidydimal epithelium, spermatid maturation and secretion of proteins by the prostate.<a href=\"#footnote_2_816\" id=\"identifier_2_816\" class=\"footnote-link footnote-identifier-link\" title=\"Stazi AV, Mantovani A. Celiac disease and its endocrine and nutritional implications on male reproduction. Minerva Medica. Jun 2004;95(3):243-54.\">2<\/a><\/li>\n<\/ul>\n<h2>How Prevalent Is Male Infertility In Celiac Disease and\/or Gluten Sensitivity?<\/h2>\n<p style=\"text-align: justify\">The celiac male has a greater risk of infertility than celiac female.<a href=\"#footnote_3_816\" id=\"identifier_3_816\" class=\"footnote-link footnote-identifier-link\" title=\"Stazi AV, Mantovani A. Celiac disease and its endocrine and nutritional implications on male reproduction. Minerva Medica. Jun 2004;95(3):243-54.\">3<\/a><\/p>\n<h2>What Are The Symptoms Of Male Infertility?<\/h2>\n<ul class=\"cp_bullet red\">\n<li>Infertility in males is marked by low, unhealthy sperm count.<\/li>\n<\/ul>\n<h2>How Does Male Infertility In Celiac Disease and\/or Gluten Sensitivity Develop?<\/h2>\n<ul class=\"cp_check red\">\n<li style=\"text-align: justify\">Infertility in males results from endocrine disorders and deficiencies of micronutrients.<a href=\"#footnote_4_816\" id=\"identifier_4_816\" class=\"footnote-link footnote-identifier-link\" title=\"Stazi AV, Mantovani A. Celiac disease and its endocrine and nutritional implications on male reproduction. Minerva Medica. Jun 2004;95(3):243-54.\">4<\/a> These micronutrients include vitamin A, vitamin D, vitamin E, zinc, and folic acid.<\/li>\n<li style=\"text-align: justify\">Nutritional deficiencies are common before treatment with gluten free diet. In 2013, a study evaluating the nutritional status of 80\u00a0Dutch patients with newly diagnosed celiac disease showed\u00a087% to have at least one nutrient deficit. Of these patients,\u00a07.5% showed deficient levels of\u00a0vitamin A, 20% for\u00a0folic acid, and 67%\u00a0for zinc deficiency.<a href=\"#footnote_5_816\" id=\"identifier_5_816\" class=\"footnote-link footnote-identifier-link\" title=\"Wierdsma NJ, van Bokhorst-de van der Schueren MA, Berkenpas M, Mulder CJ, van Bodegraven AA. Vitamin and mineral deficiencies are highly prevalent in newly diagnosed celiac disease patients. Nutrients. 2013 Sep 30;5(10):3975-92. doi: 10.3390\/nu5103975.\">5<\/a><\/li>\n<\/ul>\n<h2>Does Male Infertility Respond To Gluten Free Diet?<\/h2>\n<p style=\"text-align: justify\">Yes. Hormone alterations in Infertility in males are reversible upon start of gluten free diet.<a href=\"#footnote_2_816\" id=\"identifier_6_816\" class=\"footnote-link footnote-identifier-link\" title=\"Stazi AV, Mantovani A. Celiac disease and its endocrine and nutritional implications on male reproduction. Minerva Medica. Jun 2004;95(3):243-54.\">2<\/a>\u00a0Gluten free diet and correction of deficient dietary elements can lead to a return of fertility.<a href=\"#footnote_1_816\" id=\"identifier_7_816\" class=\"footnote-link footnote-identifier-link\" title=\"Sher KS, Jayanthi V, Probert CS, Stewart CR, Mayberry JF. Infertility, obstetric and gynaecological problems in coeliac sprue. Digestive Diseases. May-Jun 1994;12(3):186-90.\">1<\/a><\/p>\n<h2>6 Steps To Improve Male Infertility In Celiac Disease and\/or Gluten Sensitivity:<\/h2>\n<ul class=\"cp_check green\">\n<li><em><span style=\"color: #800000\"><span class=\"dropcap\"><strong>1<\/strong><\/span><\/span><strong><span style=\"color: #800000\">Remove the Trigger. Maintain a Strict, Nutritious Gluten Free Diet:<\/span><\/strong><\/em><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t<b>Treatment<\/b>. This condition responds to the complete elimination of gluten, which is the required treatment that improves both infertility and gut health.<\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li>Gut health is the foundation to restore ALL health. Restored health will enable you to maintain a strict gluten free diet, just as other life tasks will be easier.<\/li>\n<li>A strict gluten free diet means removing 100% of wheat, barley, rye and oats from the diet.<\/li>\n<li>Cutting out bread and other obvious sources of gluten is not good enough for recovery. Even 1\/8th teaspoon of flour or bread crumb is enough to sustain the inflammation that is damaging your small intestine, causing increased permeability (leaky gut) and allowing undigested gluten to enter your body where it can damage structures and function, and instigate immune inflammatory responses.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>Correct Your Individual Nutritional Needs.<\/strong><\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li>Eat foods that can replenish missing nutrients. Find them under\u00a0NUTRIENT DEFICIENCIES.<\/li>\n<li>Take nutritional supplements as needed.\u00a0Find them under\u00a0NUTRIENT DEFICIENCIES.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>Recovery<\/strong>. You should begin to feel better within a week and notice more energy as inflammation subsides and the \u00a0absorbing cells that make up the surface lining of your small intestine are better able to function.<\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li>Intestinal lining cells are replaced every 5 days. The healing process is like sunburn where the damaged surface layer of skin sloughs off and is replaced with new normal cells.<\/li>\n<li>Leaky gut normally resolves in two month after starting a gluten free diet and brings about a big improvement in health. Improvement in intestinal permeability precedes morphometric recovery (cell appearance and structure) of the small intestine in celiac disease.<a href=\"#footnote_6_816\" id=\"identifier_8_816\" class=\"footnote-link footnote-identifier-link\" title=\"Cummins AG, Thompson FM, Butler RN, et al. Improvement in intestinal permeability precedes morphometric recovery of the small intestine in coeliac disease.&nbsp;Clinical Science. Apr 2001;100(4):379-86.\">6<\/a><\/li>\n<li>The intestinal lining may take up to a year to heal.\n\t\t\t<\/div><\/div><\/li>\n<\/ul>\n<ul class=\"cp_check green\" style=\"text-align: justify\">\n<li><em><span style=\"color: #800000\"><span class=\"dropcap\"><strong>2<\/strong><\/span><\/span><strong><span style=\"color: #800000\">\u00a0Reduce Inflammation. Foods to Eat and Foods Not to Eat:<\/span><\/strong><\/em><\/li>\n<\/ul>\n<p style=\"text-align: justify\">Because gluten is inflammatory, eliminate OTHER inflammatory foods from your diet to reduce an additive effect to gluten. At the same time, try to eat foods that reduce inflammation (anti-inflammatory).<\/p>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t<strong>Here Are Major Inflammatory Food Types That Reduce Healing<\/strong>:<\/p>\n<ul class=\"cp_bullet red\" style=\"text-align: justify\">\n<li><strong>Damaging Foods<\/strong>. In susceptible persons, includes corn, dairy (cow), and soy. Lactose, the sugar in any animal milk disrupts intestinal permeability causing leaky gut.<a href=\"#footnote_7_816\" id=\"identifier_9_816\" class=\"footnote-link footnote-identifier-link\" title=\"Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease.&nbsp;Journal of Gastroenterology and Hepatology. 2003;18:479-91.\">7<\/a><\/li>\n<li><strong>Allergenic Foods<\/strong>. Includes foods that trigger the immune sytem to produce IgE antibodies. Allergy testing is the usual way to discover these offending foods.<\/li>\n<li><strong>Shelf Stable Processed Foods.\u00a0<\/strong>Includes any that contain additives and preservatives. Look for them on the nutrition label of the box or package. Additives and preservatives also disrupt intestinal permeability causing leaky gut.<a href=\"#footnote_7_816\" id=\"identifier_10_816\" class=\"footnote-link footnote-identifier-link\" title=\"Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease.&nbsp;Journal of Gastroenterology and Hepatology. 2003;18:479-91.\">7<\/a><\/li>\n<li><strong>Fats.<\/strong>\u00a0Limit deep fried foods, trans-fats, saturated fats (animal fat\/butter), and EXCESSIVE omega-6 fatty acid oils like corn oil. Rancid fats, sodium caprate (a medium chain fat), and sucrose monester fatty acid (a food grade surfactant) induce significant disruption of the intestinal barrier that causes leaky gut.<a href=\"#footnote_7_816\" id=\"identifier_11_816\" class=\"footnote-link footnote-identifier-link\" title=\"Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease.&nbsp;Journal of Gastroenterology and Hepatology. 2003;18:479-91.\">7<\/a>.<\/li>\n<li><strong>Excessive Refined White Flours\u00a0<\/strong>(bran layer removed)<strong>.\u00a0<\/strong>Includes\u00a0products made from them such as cookies, bread, cakes, pies.\u00a0Bran contains the vitamins and minerals that metabolize grains and slows the otherwise rapid entry of sugar from their digestion into the bloodstream.\u00a0Also disrupt intestinal permeability causing leaky gut.<a href=\"#footnote_7_816\" id=\"identifier_12_816\" class=\"footnote-link footnote-identifier-link\" title=\"Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease.&nbsp;Journal of Gastroenterology and Hepatology. 2003;18:479-91.\">7<\/a><\/li>\n<li><strong>Refined Sugars.\u00a0<\/strong>\u00a0Includes white sugar, corn fructose and high fructose corn syrup.<\/li>\n<li><strong>Certain Spices<\/strong>. Includes paprika and cayenne pepper which disrupt intestinal permeability causing leaky gut.<a href=\"#footnote_7_816\" id=\"identifier_13_816\" class=\"footnote-link footnote-identifier-link\" title=\"Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease.&nbsp;Journal of Gastroenterology and Hepatology. 2003;18:479-91.\">7<\/a><\/li>\n<li><strong>Alcohol and Caffeine<\/strong>. Disrupt intestinal permeability causing leaky gut.<a href=\"#footnote_7_816\" id=\"identifier_14_816\" class=\"footnote-link footnote-identifier-link\" title=\"Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease.&nbsp;Journal of Gastroenterology and Hepatology. 2003;18:479-91.\">7<\/a><\/li>\n<li><strong>Cocoa and Black\u00a0Tea<\/strong>\u00a0increase blood sugar.<\/li>\n<li><strong>Rosemary.<\/strong>\u00a0Increases blood sugar levels and should not be used by persons with insulin resistance or diabetes. \n\t\t\t<\/div><\/div><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t<strong>Here Are Important Anti-Inflammatory Food Types to Promote Health<\/strong>:<\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li><strong>Fruits<\/strong>.\u00a0Contain ample amounts of vitamins, minerals and phytochemicals which are\u00a0naturally occuring components in plants that detoxify toxins, carcinogens (reducing the risk by 50%) and mutagens.<\/li>\n<li><strong>Non-Starchy Vegetables.<\/strong>\u00a0Support intestinal integrity and provide ample amounts of vitamins, minerals and phytochemicals. Includes green leafy vegetables such as lettuce and kale, also onion, broccoli, garlic, and others.<\/li>\n<li><strong>High Quality Complex Carbohydrates<\/strong>. Provide vitamins, minerals, and fiber while boosting serotonin levels to help you relax and feel calm. Includes whole grains, legumes, and root vegetables such as carrots, parsnips, sweet potatoes, turnips, red beets, and others.<\/li>\n<li><strong>Antioxidants<\/strong>. Protect the body from inflammatory oxidant molecules that continually occur and\u00a0help us handle stress and reduce irritability. Includes vitamin C-containing foods such as lemon, grapefruit, apricot, Brussels sprouts and strawberries, and others. Also, includes vitamin E-containing foods such as\u00a0nuts, seeds, avocado, olive oil, and others. Cocoa is good, too.<\/li>\n<li><strong>Omega-3 Fatty Acids<\/strong>. Balance opposing omega-6 fatty acids and bad fats. Fish sources includes tuna, salmon, cod, and others. Plants sources include flax, chia seeds, canola oil, and others.<\/li>\n<li><strong>Probiotics.\u00a0<\/strong>Supply normal microbes needed for colon health and health of the body such as these fermented foods: yogurt, kefir, and unpasteurized apple cider vinegar.<\/li>\n<li><strong>Prebiotics\/ High Fiber Foods<\/strong>. \u00a0Food with fiber keeps our population of colonic microbes healthy.<\/li>\n<li><strong>Protective Herbs and Spices<\/strong>. \u00a0See below #6 below for examples.\n\t\t\t<\/div><\/div><\/li>\n<\/ul>\n<ul class=\"cp_check green\" style=\"text-align: justify\">\n<li><em><span style=\"color: #800000\"><strong><span class=\"dropcap\">3<\/span>\u00a0Information Sheet You Can Take to Your Doctor or Other Health Professional:<\/strong><\/span><\/em><\/li>\n<\/ul>\n<p style=\"text-align: justify\">Click here.<\/p>\n<ul class=\"cp_check green\" style=\"text-align: justify\">\n<li><span style=\"color: #800000\"><strong><em><span class=\"dropcap\">4<\/span>\u00a0Manage Your Medications\u00a0Safely<\/em>:<\/strong><\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t\n<p style=\"text-align: justify\">Certain medications deplete vitamin A, Vitamin D, vitamin E, zinc, and folic acid. Ask your doctor or pharmacist about this possible adverse effect if you are taking any of the drugs listed below.\u00a0<strong>Do not stop prescribed medications without supervision.<\/strong><\/p>\n<p style=\"text-align: justify\">\u00a0This is not a complete listing.<\/p>\n<p><strong>ANTACIDS \/ ULCER MEDICATIONS<\/strong><\/p>\n<ul class=\"cp_bullet blue\">\n<li>Pepcid\u00ae, Tagamet\u00ae, Zantac\u00ae deplete Folic Acid, Vitamin A,Vitamin D, Zinc.<\/li>\n<li>Magnesium and Aluminum Antacid preparations (Gaviscon\u00ae, Maalox\u00ae, Mylanta\u00ae) deplete\u00a0Folic Acid, Vitamin A,Vitamin D, Zinc.<\/li>\n<li>Alka Seltzer\u00ae, Baking Soda deplete Folic Acid.<\/li>\n<\/ul>\n<p><strong>ANTIBIOTICS\u00a0<\/strong>disrupt intestinal permeability which complicates celiac disease.<\/p>\n<ul class=\"cp_bullet blue\">\n<li>Gentomycin, Neomycin, Streptomycin, Cephalosporins, Penicillins\u00a0deplete\u00a0B Vitamins.<\/li>\n<li>\u00a0Tetracyclines deplete Zinc.<\/li>\n<li>Cipro depletes Zinc.<\/li>\n<li>Penicillins deplete Folic Acid.<a href=\"#footnote_8_816\" id=\"identifier_15_816\" class=\"footnote-link footnote-identifier-link\" title=\"https:\/\/umm.edu\/health\/medical\/altmed\/depletion\/antibiotic-medications-penicillin-derivatives.\">8<\/a><\/li>\n<li>Erythromycin\u00a0depletes Folic Acid.<a href=\"#footnote_9_816\" id=\"identifier_16_816\" class=\"footnote-link footnote-identifier-link\" title=\"http:\/\/umm.edu\/health\/medical\/altmed\/depletion\/antibiotic-medications-macrolides\">9<\/a><\/li>\n<\/ul>\n<p><strong>ANTI-INFLAMMATORIES<\/strong>\u00a0disrupt intestinal permeability which complicates celiac disease.<\/p>\n<ul class=\"cp_bullet blue\">\n<li>Corticosteroids (Prednisone, Medrol\u00ae, Aristocort\u00ae, Decadron) deplete Vitamin D, Zinc, Folic Acid.<\/li>\n<li>NSAIDS (Motrin\u00ae, Aleve\u00ae, Advil\u00ae, Anaprox\u00ae, Dolobid\u00ae, Feldene\u00ae, Naprosyn\u00ae and others) deplete\u00a0Folic acid.<\/li>\n<li>Aspirin and Salicylates deplete Folic acid.<\/li>\n<\/ul>\n<p><strong>ANTICONVULSANTS<\/strong><\/p>\n<ul class=\"cp_bullet blue\">\n<li>Phenobarbital and Barbituates; and Dilantin\u00ae, Tegretol\u00ae, Mysoline\u00ae, Depakane\/Depacon\u00ae deplete Vitamin D, Folic Acid, Zinc.<\/li>\n<\/ul>\n<p><strong>ANTIVIRAL AGENTS<\/strong><\/p>\n<ul class=\"cp_bullet blue\">\n<li>Zidovudine (Retrovir\u00ae, AZT and other related drugs) deplete Zinc.<\/li>\n<\/ul>\n<p><strong>BRONCHODILATORS<\/strong><\/p>\n<ul class=\"cp_bullet blue\">\n<li>Inhaled corticosteroid inhalers (Flovent, Pulmicort and others) that are breathed in on a daily basis\u00a0as a long term therapy to reduce inflammation in airways deplete Vitamin D, B vitamins.<\/li>\n<\/ul>\n<p><strong>CARDIOVASCULAR DRUGS<\/strong><\/p>\n<ul class=\"cp_bullet blue\">\n<li>Antihypertensives (Catapres\u00ae, Aldomet) deplete Zinc.<\/li>\n<li>ACE Inhibitors (Capoten\u00ae, Vasotec\u00ae, Monopril\u00ae and others) deplete Zinc.<\/li>\n<\/ul>\n<p><strong>CHOLESTEROL DRUGS<\/strong><\/p>\n<ul class=\"cp_bullet blue\">\n<li>Colestid\u00ae and Questran\u00ae deplete Vitamin A, Vitamin D, Vitamin E, Folic Acid,.<\/li>\n<\/ul>\n<p><strong>DIABETIC DRUGS\u00a0<\/strong><\/p>\n<ul class=\"cp_bullet blue\">\n<li>Metformin\u00ae depletes\u00a0Coenzyme Q10, Folic acid.<\/li>\n<\/ul>\n<p><strong>DIURETICS<\/strong><\/p>\n<ul class=\"cp_bullet blue\">\n<li>Thiazide Diuretics (Hydrochlorothiazide, Enduron\u00ae, Diuril\u00ae, Lozol\u00ae, Zaroxolyn\u00ae, Hygroton\u00ae and others) deplete Zinc.<\/li>\n<li>Loop Diuretics (Lasix\u00ae, Bumex\u00ae, Edecrin\u00ae) deplete Zinc.<\/li>\n<li>Potassium Sparing Diuretics (Midamor\u00ae, Aldactone\u00ae, Dyrenium\u00ae and others) deplete Folic Acid, Zinc.<\/li>\n<\/ul>\n<p><strong>FEMALE HORMONES<\/strong>\u00a0disrupt intestinal permeability which complicate celiac disease.<\/p>\n<ul class=\"cp_bullet blue\">\n<li>Oral Contraceptives (Norinyl\u00ae, Ortho-Novum\u00ae, Triphasil\u00ae, and others) deplete Folic Acid, Zinc.<\/li>\n<li>Oral Estrogen\/Hormone Replacement (Evista\u00ae, Prempro\u00ae, Premarin\u00ae, Estratab\u00ae and others) deplete Folic Acid, Zinc.<\/li>\n<\/ul>\n<p><strong>LAXATIVES<\/strong><\/p>\n<ul class=\"cp_bullet blue\">\n<li>Metamucil, FiberCon, Citrucel, Colace, Glycolax, Milk of magnesia, Dulcolax deplete: Vitamins A, Vitamin D, Vitamin E.<\/li>\n<\/ul>\n<p><strong>WEIGHT LOSS DRUGS THAT BIND FAT\u00a0<\/strong>also interfere with absorption of some nutrients.<\/p>\n<ul class=\"cp_bullet blue\">\n<li>Zenicol (Orlistat\u00ae) depletes Vitamin A, Vitamin D, Vitamin E.<\/li>\n<\/ul>\n<p style=\"text-align: justify\">\n\t\t\t<\/div><\/div>\n<ul class=\"cp_check green\" style=\"text-align: justify\">\n<li><em><span style=\"color: #800000\"><strong><span class=\"dropcap\">5<\/span>Nutritional Supplements To Help Correct Deficiencies:<\/strong><\/span><\/em><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t\n<p style=\"text-align: justify\">The type and quantity of nutritional supplements that may be needed depend on which nutrients are deficient.<\/p>\n<ul class=\"cp_bullet orange\" style=\"text-align: justify\">\n<li>Multivitamin\/mineral combination that provides 100% once a day is useful to improve overall nutrient levels. This is a safe dose, but always check with your doctor to avoid interactions with medications.<\/li>\n<li>Folic acid\u00a0as prescribed following blood test for status.<\/li>\n<li>Vitamin D3 as prescribed following blood test for status.<\/li>\n<li>Vitamin A as prescribed following blood test for status.<\/li>\n<li>Vitamin E as prescribed following blood test for status.<\/li>\n<li>Zinc as prescribed but do not take at same time as calcium because they compete for absorption.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>Storage Note<\/strong>:\u00a0<em>Store container tightly sealed, away from heat, moisture and direct light to avoid loss of potency. That is, in a safe kitchen cabinet &#8211; not in the bathroom or on the kitchen table<\/em>.\n\t\t\t<\/div><\/div>\n<ul class=\"cp_check green\" style=\"text-align: justify\">\n<li><span style=\"color: #800000\"><em><strong><span class=\"dropcap\">6<\/span>Manage Natural Remedies:\u00a0<\/strong><\/em><\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t<strong>Hydration<\/strong>:<\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li>Eight glasses of water are recommended per day unless there is a contraindication such as kidney or heart disease. The Institute of Medicine recommends approximately 2.7 liters (91 ounces) of total water, from all beverages and foods, each day for women and 3.7 liters (125 ounces) daily of total water for men.<\/li>\n<li>If you are thirsty, drink water. Add fresh, squeezed lemon to water. Lemon is anti-inflammatory, alkalizing and provides vitamin C.<\/li>\n<li>Hydration Test: Urine should be pale yellow. Fingertips should be plump, without pruning but this may not be reliable when fingers are swollen with edema. Lips should be plump, without puckering. The feeling of thirst can be unreliable.<\/li>\n<li>What is wrong with soda, coffee, tea, and alcohol? These drinks are dehydrating, increase acid, and deplete nutrients.\n\t\t\t<\/div><\/div><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t<strong>Carminatives.\u00a0<\/strong>The following \u00a0anti-inflammatory\u00a0plant sources called carminitives help heal the digestive tract. They also tone the digestive muscles which improves peristalsis, thus aiding in the expulsion of gas from the stomach and intestine to relieve digestive colic and gastric discomfort.<\/p>\n<p style=\"text-align: justify\"><strong>Carminative Food Remedies<\/strong>:<\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li>Raspberry.<\/li>\n<li>Carrot is also a cleansing digestive tonic.<\/li>\n<li>Grape is also bile stimulating and a cleansing remedy for sluggish digestion and laxative.<\/li>\n<li>Redbeets also stimulate and improve digestion and are easily digested.<\/li>\n<li>Cabbage also stimulates and improves digestion and is also a liver decongestant.<\/li>\n<li>Lettuce also stimulates and improves digestion and is also an alterative, meaning it improves the function of organs involved with the digestion and excretion of waste products to bring about a gradual change.<\/li>\n<li>Potatoes are antispasmodic (due to atropine like properties) and a liver remedy.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>Carminative Herb Remedies:<\/strong><\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li>Sage is also a digestive, astringent, bile stimulant and energy tonic that heals the mucosa. \u00a0Drink as tea or use in cooking.<\/li>\n<li>Chamomile, lemon balm, and fennel, (as a tea) also help relieve nervous tension.<\/li>\n<li>Parsley also relieves indigestion.<\/li>\n<li>Rosemary as a tea and in cooking also is a nervous system tonic for stress and fatigue, bile stimulant, and can relieve headaches and indigestion. However, because it increases blood sugar levels, it should not be used by persons with insulin resistance or diabetes.<\/li>\n<li>Thyme is also soothing remedy useful for stimulating digestion of rich, fatty foods.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>Carminative Spice Remedies:<\/strong><\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li>Cloves are also antispasmodic.<\/li>\n<li>Nutmeg is also useful for indigestion.<\/li>\n<li>Ginger.\n\t\t\t<\/div><\/div><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t<strong>Exercise Helps<\/strong>:<\/p>\n<p style=\"text-align: justify\">Exercise improves circulation and rids the body of toxins.<\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li>Walking is aerobic exercise that reconditions the whole body to improve stamina.\u00a0Read more about<a href=\"https:\/\/glutenfreeworks.com\/health\/2014\/07\/08\/fitness-guide\/\">\u00a0Exercise and Fitness<\/a>.<\/li>\n<li>Weight training builds muscle.\u00a0Read more about\u00a0<a href=\"https:\/\/glutenfreeworks.com\/health\/2014\/07\/08\/fitness-guide\/\">Exercise and Fitness<\/a>.<\/li>\n<li>Stretching improves flexibilty.\u00a0Read more about\u00a0<a href=\"https:\/\/glutenfreeworks.com\/health\/2014\/07\/08\/fitness-guide\/\">Exercise and Fitness<\/a>.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>Note<\/strong>: Exercise is important, but the amount and type of exercise undertaken depends on your health. Your first priority is to heal. \n\t\t\t<\/div><\/div>\n<h2 style=\"text-align: justify\">What Do Medical Research Studies Tell About Male Infertility In Celiac Disease and\/or Gluten Sensitivity?<\/h2>\n<h4><strong>RESEARCH STUDY SUMMARIES<\/strong><\/h4>\n<p style=\"text-align: justify\"><b>\u201cVitamin and mineral deficiencies are highly prevalent in newly diagnosed celiac disease patients.\u201d<\/b> This study aiming to assess the nutritional and vitamin\/mineral status of current &#8220;early diagnosed&#8221; untreated adult celiac disease (CD) patients in the Netherlands found that vitamin\/mineral deficiencies are still common in newly &#8220;early diagnosed&#8221; CD-patients, even though the prevalence of obesity at initial diagnosis is rising.. Eighty newly diagnosed adult CD-patients were included and a comparable sample of 24 healthy Dutch subjects was added to compare vitamin concentrations.<\/p>\n<p style=\"text-align: justify\">Nutritional status and serum concentrations of folic acid,\u00a0vitamin A, B\u2086, B\u2081\u2082, and (25-hydroxy) D, zinc, haemoglobin (Hb) and ferritin were determined \u00a0(before prescribing gluten free diet). Almost all CD-patients (87%) had at least one value below the lower limit of reference. Specifically, for\u00a0vitamin A, 7.5% of patients showed deficient levels, for vitamin B\u2086 14.5%, folic acid 20%, and vitamin B\u2081\u2082 19%. Likewise, zinc deficiency was observed in 67% of the CD-patients, 46% had decreased iron storage, and 32% had anaemia. Overall, 17% were malnourished (&gt;10% undesired weight loss), 22% of the women were underweight (Body Mass Index (BMI) &lt; 18.5), and 29% of the patients were overweight (BMI &gt; 25). Vitamin deficiencies were barely seen in healthy controls, with the exception of vitamin B\u2081\u2082. Vitamin\/mineral deficiencies were counter-intuitively not associated with a (higher) grade of histological intestinal damage or (impaired) nutritional status. Extensive nutritional assessments seem warranted to guide nutritional advices and follow-up in CD treatment.<a href=\"#footnote_10_816\" id=\"identifier_17_816\" class=\"footnote-link footnote-identifier-link\" title=\"Wierdsma NJ, van Bokhorst-de van der Schueren MA, Berkenpas M, Mulder CJ, van Bodegraven AA. Vitamin and mineral deficiencies are highly prevalent in newly diagnosed celiac disease patients. Nutrients. 2013 Sep 30;5(10):3975-92. doi: 10.3390\/nu5103975.\">10<\/a><\/p>\n<p style=\"text-align: justify\"><strong>\u201cOxidative stress in subjects affected by celiac disease.\u201d<\/strong> This study investigating the role of oxidative stress in celiac disease demonstrated the level of markers for vitamin E were significantly lower in celiac disease than in contols.<a href=\"#footnote_11_816\" id=\"identifier_18_816\" class=\"footnote-link footnote-identifier-link\" title=\"Odetti P, Valentini S, Aragno I, Garibaldi S, Pronzato MA, Rolandi E, Barreca T. Oxidative stress in subjects affected by celiac disease. Free Radical Research. Jul 1998;29(1):17-24.\">11<\/a><\/p>\n<p style=\"text-align: justify\">\u201c<strong>Male gonadal function in coeliac disease: III. Pituitary regulation<\/strong>.\u201d This study investigating pituitary regulation of gonadal function in treated and untreated male patients with celiac disease demonstrated a derangement of pituitary regulation of gonadal function. Exaggerated responses of FSH (89%) and LH (49%) to LHRH were found in celiacs with sub-total villous atrophy and were commonly found when basal gonadotropin concentrations were normal. LH response was closely linked\u00a0to jejunal morphology.<a href=\"#footnote_12_816\" id=\"identifier_19_816\" class=\"footnote-link footnote-identifier-link\" title=\"Farthing MJ, Rees LH, Edwards CR, Dawson AM. Male gonadal function in coeliac disease: III. Pituitary regulation. Clinical Endocrinology. Dec 1983;19(6):661-71.\">12<\/a><\/p>\n<p style=\"text-align: justify\">\u201c<strong>Male gonadal function in coeliac disease: 2. Sex hormones<\/strong>.\u201d This study investigating increased plasma testosterone and free testosterone index, reduced dihydro-testosterone, and raised serum luteinising hormone related to jejunal morphology, fertility, semen quality, and sexual function in 41 celiac males demonstrated a pattern indicative of androgen resistance specific to celiac disease. As jejunal morphology improved hormone levels appeared to return to normal. This specific combination of abnormalities was not present in any of the disease control groups and, to our knowledge androgen resisance has not been described previously in any other non-endocrine disorder.<a href=\"#footnote_13_816\" id=\"identifier_20_816\" class=\"footnote-link footnote-identifier-link\" title=\"Farthing MJ, Rees LH, Edwards CR, Dawson AM. Male gonadal function in coeliac disease: 2. Sex hormones. Gut. Feb 1983;24(2):127-35.\">13<\/a><\/p>\n<p style=\"text-align: justify\">\n<ol class=\"footnotes\"><li id=\"footnote_1_816\" class=\"footnote\">Sher KS, Jayanthi V, Probert CS, Stewart CR, Mayberry JF. Infertility, obstetric and gynaecological problems in coeliac sprue. <em>Digestive Diseases<\/em>. May-Jun 1994;12(3):186-90.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_1_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_7_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_2_816\" class=\"footnote\">Stazi AV, Mantovani A. Celiac disease and its endocrine and nutritional implications on male reproduction. <em>Minerva Medica.<\/em> Jun 2004;95(3):243-54.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_2_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_6_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_3_816\" class=\"footnote\">Stazi AV, Mantovani A. Celiac disease and its endocrine and nutritional implications on male reproduction. <em>Minerva Medica<\/em>. Jun 2004;95(3):243-54.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_3_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_4_816\" class=\"footnote\">Stazi AV, Mantovani A. Celiac disease and its endocrine and nutritional implications on male reproduction. Minerva Medica. Jun 2004;95(3):243-54.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_4_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_5_816\" class=\"footnote\">Wierdsma NJ, van Bokhorst-de van der Schueren MA, Berkenpas M, Mulder CJ, van Bodegraven AA. Vitamin and mineral deficiencies are highly prevalent in newly diagnosed celiac disease patients. <em>Nutrients<\/em>. 2013 Sep 30;5(10):3975-92. doi: 10.3390\/nu5103975.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_5_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_6_816\" class=\"footnote\">Cummins AG, Thompson FM, Butler RN, et al. Improvement in intestinal permeability precedes morphometric recovery of the small intestine in coeliac disease.\u00a0<em>Clinical Science<\/em>. Apr 2001;100(4):379-86.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_8_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_7_816\" class=\"footnote\">Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease.\u00a0<em>Journal of Gastroenterology and Hepatology<\/em>. 2003;18:479-91.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_9_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_10_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_11_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_12_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_13_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_14_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_8_816\" class=\"footnote\">https:\/\/umm.edu\/health\/medical\/altmed\/depletion\/antibiotic-medications-penicillin-derivatives.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_15_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_9_816\" class=\"footnote\">http:\/\/umm.edu\/health\/medical\/altmed\/depletion\/antibiotic-medications-macrolides<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_16_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_10_816\" class=\"footnote\">Wierdsma NJ, van Bokhorst-de van der Schueren MA, Berkenpas M, Mulder CJ, van Bodegraven AA. Vitamin and mineral deficiencies are highly prevalent in newly diagnosed celiac disease patients. <i>Nutrients<\/i>. 2013 Sep 30;5(10):3975-92. doi: 10.3390\/nu5103975.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_17_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_11_816\" class=\"footnote\">Odetti P, Valentini S, Aragno I, Garibaldi S, Pronzato MA, Rolandi E, Barreca T. Oxidative stress in subjects affected by celiac disease. <em>Free Radical Research<\/em>. Jul 1998;29(1):17-24. <span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_18_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_12_816\" class=\"footnote\">Farthing MJ, Rees LH, Edwards CR, Dawson AM. Male gonadal function in coeliac disease: III. Pituitary regulation. <em>Clinical Endocrinology<\/em>. Dec 1983;19(6):661-71.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_19_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_13_816\" class=\"footnote\">Farthing MJ, Rees LH, Edwards CR, Dawson AM. Male gonadal function in coeliac disease: 2. Sex hormones. <em>Gut<\/em>. Feb 1983;24(2):127-35.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_20_816\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><\/ol>","protected":false},"excerpt":{"rendered":"<p>What Is Infertility in Males? Infertility in males is characterized by inability to either produce sperm or to produce viable sperm or mobile sperm resulting in prohibiting fertilization of the female ovum (egg). To the left is a false-colour scanning electron micrograph of seminiferous tubules in the human testis (cross section), the site of production &#8230;<\/p>\n","protected":false},"author":29,"featured_media":7019,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[4,105,167,974,225,226,151,111,123,109],"tags":[334,916,993,917,1978,992],"class_list":["post-816","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-conditions-2","category-folic-acid","category-omega-6-fatty-acids","category-symptoms","category-male","category-testes","category-vitamin-a","category-vitamin-d","category-vitamin-e","category-zinc","tag-hyperprolactinemia","tag-infertility","tag-pituitary-hormone-dysfunction","tag-sperm-abnormalities","tag-testes","tag-testosterone"],"_links":{"self":[{"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/posts\/816","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/users\/29"}],"replies":[{"embeddable":true,"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/comments?post=816"}],"version-history":[{"count":15,"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/posts\/816\/revisions"}],"predecessor-version":[{"id":18833,"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/posts\/816\/revisions\/18833"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/media\/7019"}],"wp:attachment":[{"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/media?parent=816"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/categories?post=816"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/tags?post=816"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}