{"id":479,"date":"2016-12-31T14:29:14","date_gmt":"2016-12-31T19:29:14","guid":{"rendered":"http:\/\/www.mynutriguide.com\/?p=479"},"modified":"2020-07-11T10:38:15","modified_gmt":"2020-07-11T14:38:15","slug":"systemic-lupus-erythematosus-2","status":"publish","type":"post","link":"https:\/\/glutenfreeworks.com\/health\/systemic-lupus-erythematosus-2\/","title":{"rendered":"Systemic Lupus Erythematosus\u00a0"},"content":{"rendered":"
\"Image<\/a>

Image showing butterfly rash typical of SLE. Courtesy JAMA.<\/em><\/p><\/div>\n

What Is Systemic Lupus Erythematosus?<\/h2>\n

S<\/span>ystemic lupus erythematosus\u00a0(SLE) is a chronic autoimmune inflammatory disease that is characterized by involvement of multiple organs due to\u00a0the production of antibodies to components of the cell nucleus.1<\/a> SLE has an unpredictable course of acute flare-ups and remissions.<\/p>\n

Severity depends on the extent of organs affected with skin and nail involvement, called discoid lupus, being the least serious and inflammmation of the kidney, called lupus nephritis, being the worst.<\/p>\n

Nevetheless, a classic presentation is development of a rash over the cheeks and nose that resembles a butterfy with wings spread hence the name “butterfly rash.”<\/p>\n

Symptoms are many and varied depending on the tissues affected and\u00a0are often not specific, for example hair loss has a variety of causes. Symptoms can be confused by co-existence with other autoimmune disease such as Sjogren’s syndrome.<\/p>\n

Systemic lupus erythematosus should be managed by a specialist. Symptoms can be controlled\u00a0wi<\/span>th steroid therapy,\u00a0<\/span>but this disease can be a cause of premature death \u00a0mainly from active disease, organ failure (e.g., kidneys), infection, or cardiovascular disease from accelerated atherosclerosis.<\/span><\/p>\n

Certain common medicines known to cause drug-induced lupus are:<\/p>\n