{"id":324,"date":"2014-12-30T17:20:51","date_gmt":"2014-12-30T22:20:51","guid":{"rendered":"http:\/\/www.mynutriguide.com\/?p=324"},"modified":"2020-07-11T10:50:30","modified_gmt":"2020-07-11T14:50:30","slug":"adenocarcinoma-of-small-intestine","status":"publish","type":"post","link":"https:\/\/glutenfreeworks.com\/health\/adenocarcinoma-of-small-intestine\/","title":{"rendered":"Adenocarcinoma Of Small Intestine (Cancer)"},"content":{"rendered":"<div id=\"attachment_6009\" style=\"width: 310px\" class=\"wp-caption alignleft\"><a href=\"https:\/\/glutenfreeworks.com\/health\/wp-content\/uploads\/sites\/10\/13392948018083-small.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-6009\" class=\"size-medium wp-image-6009\" src=\"https:\/\/glutenfreeworks.com\/health\/wp-content\/uploads\/sites\/10\/13392948018083-small-300x198.jpg\" alt=\"Section of small bowel surgically removed for adenocarcinoma that grew through the wall. By: CDC\/ Dr. Edwin P. Ewing, Jr.\" width=\"300\" height=\"198\" srcset=\"https:\/\/glutenfreeworks.com\/health\/wp-content\/uploads\/sites\/10\/13392948018083-small-300x198.jpg 300w, https:\/\/glutenfreeworks.com\/health\/wp-content\/uploads\/sites\/10\/13392948018083-small.jpg 586w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><p id=\"caption-attachment-6009\" class=\"wp-caption-text\">Section of small bowel surgically removed for adenocarcinoma that grew through the wall. <em>By: CDC\/ Dr. Edwin P. Ewing, Jr.<\/em><\/p><\/div>\n<h2>What Is Adenocarcinoma Of Small Intestine?<\/h2>\n<p style=\"text-align: justify\"><span class=\"dropcap\">A<\/span>denocarcinomas are malignant tumors, or cancer, of the small bowel arising out of glandular tissue. They fall in the category of rare neoplasm, comprising only 3% of all gastrointestinal malignancies.<\/p>\n<p style=\"text-align: justify\"><span style=\"line-height: 1.5em\">Primary adenocarcinoma is the most common histological (cell) subtype constituting 35\u201350% of cases.<a href=\"#footnote_1_324\" id=\"identifier_1_324\" class=\"footnote-link footnote-identifier-link\" title=\"Benhammane H,&nbsp;El M&rsquo;rabet FZ,&nbsp;Serhouchni KI,&nbsp;El yousfi M,&nbsp;Charif I,&nbsp;Toughray I, et al. Small Bowel Adenocarcinoma Complicating Coeliac Disease: A Report of Three Cases and the Literature Review.&nbsp;Case Rep Oncol Med. 2012; 2012: 935183. Published online 2012 December 1. doi: 10.1155\/2012\/935183\">1<\/a>\u00a0<\/span><\/p>\n<p style=\"text-align: justify\"><strong>Q:<\/strong> What does adenocarcinoma look like?<\/p>\n<p style=\"text-align: justify\"><strong>A:<\/strong> Adenocarcinoma\u00a0may manifest as strictures, nodules, excavating masses, or annular lesions.<a href=\"#footnote_2_324\" id=\"identifier_2_324\" class=\"footnote-link footnote-identifier-link\" title=\"Ramachandran I, Sinha R, Rajesh A, Verma R. Multidetector row CT of small bowel tumors. &nbsp;Clinical Radiology. 2007; 62:607-614.\">2<\/a><\/p>\n<h2>What Is Adenocarcinoma Of Small Intestine In Celiac Disease and\/or Gluten Sensitivity?<\/h2>\n<p><!--more--><\/p>\n<ul class=\"cp_check red\">\n<li style=\"text-align: justify\"><strong>Relationship between adenocarcinoma of small intestine\u00a0and celiac disease.<\/strong> Adenocarcinoma of the small intestine is a severe complication of celiac disease.<\/li>\n<li style=\"text-align: justify\"><strong>Relationship between adenocarcinoma of small intestine\u00a0and risk.\u00a0<\/strong>Celiac disease is associated with an increased risk of\u00a0small intestinal adenocarcinoma which is 82 times more common in patients with celiac disease than in the normal population.<a href=\"#footnote_3_324\" id=\"identifier_3_324\" class=\"footnote-link footnote-identifier-link\" title=\"Benhammane H,&nbsp;El M&rsquo;rabet FZ,&nbsp;Serhouchni KI,&nbsp;El yousfi M,&nbsp;Charif I,&nbsp;Toughray I, et al. Small Bowel Adenocarcinoma Complicating Coeliac Disease: A Report of Three Cases and the Literature Review. Case Rep Oncol Med. 2012; 2012: 935183. Published online 2012 December 1. doi: 10.1155\/2012\/935183\">3<\/a><\/li>\n<\/ul>\n<h2>How Prevalent Is Adenocarcinoma Of Small Intestine In Celiac Disease and\/or Gluten Sensitivity?<\/h2>\n<p style=\"text-align: justify\">Adenocarcinoma of small intestine has increased frequency in celiac disease patients.<a href=\"#footnote_4_324\" id=\"identifier_4_324\" class=\"footnote-link footnote-identifier-link\" title=\"Ferguson A, Kingstone K. Coeliac disease and malignancies. Acta Paediatr Suppl. 1996 May;412:78-81.\">4<\/a><\/p>\n<p style=\"text-align: justify\">Research shows a \u00a060 to 80 fold risk in patients with untreated celiac disease with significantly increased morbidity (illness).<a href=\"#footnote_5_324\" id=\"identifier_5_324\" class=\"footnote-link footnote-identifier-link\" title=\"Rampertab SD, Fleischauer A, Neugut AI, Green PH. Risk of duodenal adenoma in celiac disease. Scandanavian Journal of Gastroentorology. Aug 2003;38(8):831-3.\">5<\/a><\/p>\n<h2><strong><a href=\"https:\/\/glutenfreeworks.com\/health\/wp-content\/uploads\/sites\/10\/istock-photo-19922107-intestinal-tumor.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft  wp-image-8410\" style=\"margin-left: 5px;margin-right: 5px\" src=\"https:\/\/glutenfreeworks.com\/health\/wp-content\/uploads\/sites\/10\/istock-photo-19922107-intestinal-tumor-300x225.jpg\" alt=\"Small Intestinal Tumor\" width=\"241\" height=\"182\" srcset=\"https:\/\/glutenfreeworks.com\/health\/wp-content\/uploads\/sites\/10\/istock-photo-19922107-intestinal-tumor-300x225.jpg 300w, https:\/\/glutenfreeworks.com\/health\/wp-content\/uploads\/sites\/10\/istock-photo-19922107-intestinal-tumor.jpg 800w\" sizes=\"auto, (max-width: 241px) 100vw, 241px\" \/><\/a><\/strong>What Are The Symptoms Of Adenocarcinoma Of Small Intestine?<\/h2>\n<p style=\"text-align: justify\">Adenocarcinoma of small intestine in celiac disease is marked by these symptoms:<\/p>\n<ul class=\"cp_bullet red\">\n<ul>\n<ul>\n<ul>\n<ul>\n<ul>\n<ul>\n<li><span style=\"font-size: 13px;line-height: 1.5em\">Occult bleeding (not visible).<\/span><\/li>\n<li><span style=\"font-size: 13px;line-height: 1.5em;text-align: justify\">Bowel changes.<\/span><\/li>\n<li><span style=\"font-size: 13px;line-height: 1.5em;text-align: justify\">Unexplained upper abdominal pain that may be generalized or localized.<\/span><\/li>\n<li><span style=\"font-size: 13px;line-height: 1.5em;text-align: justify\">Weight loss.<\/span><\/li>\n<li><span style=\"font-size: 13px;line-height: 1.5em;text-align: justify\">Anemia. \u00a0<\/span><\/li>\n<\/ul>\n<\/ul>\n<\/ul>\n<\/ul>\n<\/ul>\n<\/ul>\n<\/ul>\n<p><span style=\"text-align: justify;line-height: 1.5em\">Complications are\u00a0bowel obstruction or perforation.<a href=\"#footnote_6_324\" id=\"identifier_6_324\" class=\"footnote-link footnote-identifier-link\" title=\"Ramachandran I, Sinha R, Rajesh A, Verma R. Multidetector row CT of small bowel tumors. &nbsp;Clinical Radiology. 2007; 62:607-614.\">6<\/a><\/span><\/p>\n<h2>How Does Adenocarcinoma Of Small Intestine Develop In Celiac Disease and\/or Gluten Sensitivity?<\/h2>\n<ul class=\"cp_check red\">\n<li style=\"text-align: justify\">Adenocarcinoma of small intestine in celiac disease may result from cellular damage involving chronic gluten exposure and deficiencies due to malabsorption in celiac disease.<\/li>\n<li style=\"text-align: justify\">Nutritional deficiencies that contribute include omega-3 fatty acids, selenium, thiamin, vitamin B12 and niacin.<\/li>\n<li style=\"text-align: justify\">A study by Hinks et.al investigating selenium concentrations in whole blood, plasma, and leukocytes of patients with biopsy confirmed celiac disease, who were clinically well and receiving gluten free diet, demonstrated significantly lower concentrations than controls, probably indicating a decrease in the body content of selenium. As a protective role for selenium against cancer has been postulated, the importance of this unexpected observation of lowered tissue concentrations of selenium requires further investigation.<a href=\"#footnote_7_324\" id=\"identifier_7_324\" class=\"footnote-link footnote-identifier-link\" title=\"Hinks LJ, Inwards KD, Lloyd B, Clayton BE. Body content of selenium in coeliac disease.&nbsp;British Medical Journal.&nbsp;Jun 23, 1984;288(6434):1862-3.\">7<\/a><\/li>\n<\/ul>\n<h2>Does Adenocarcinoma Of Small Intestine Respond To Gluten-Free Diet?<\/h2>\n<p style=\"text-align: justify\">Yes. Gluten free diet is protective against celiac disease-related adenocarcinoma of the small intestine.<a href=\"#footnote_8_324\" id=\"identifier_8_324\" class=\"footnote-link footnote-identifier-link\" title=\"Green PH, Fleischauer AT, Bhagat G, Goyal R, Jabri B, Neugut AI. Risk of malignancy in patients with celiac disease. American Journal of Medicine. Aug 15, 2003;115(3):191-5.\">8<\/a><\/p>\n<h2>6 Steps To Improve Adenocarcinoma Of \u00a0Small Intestine\u00a0In Celiac Disease and\/or Gluten Sensitivity:<\/h2>\n<ul class=\"cp_check green\">\n<li style=\"text-align: justify\"><em><span style=\"color: #800000\"><span class=\"dropcap\"><strong>1<\/strong><\/span><\/span><strong><span style=\"color: #800000\">Remove the Trigger. Maintain a Strict, Nutritious Gluten Free Diet:<\/span><\/strong><\/em><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t<b>Treatment<\/b>. This condition responds to the complete elimination of gluten, which is the required treatment that improves both cancer risk and gut health.<\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li>Gut health is the foundation to restore ALL health. Restored health will enable you to maintain a strict gluten free diet, just as other life tasks will be easier.<\/li>\n<li>A strict gluten free diet means removing 100% of wheat, barley, rye and oats from the diet.<\/li>\n<li>Cutting out bread and other obvious sources of gluten is not good enough for recovery. Even 1\/8th teaspoon of flour or bread crumb is enough to sustain the inflammation that is damaging your small intestine, causing increased permeability (leaky gut) and allowing undigested gluten to enter your body where it can damage structures and function, and instigate immune inflammatory responses.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>Correct Your Individual Nutritional Needs.<\/strong><\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li>Eat foods that can replenish missing nutrients. Find them under\u00a0NUTRIENT DEFICIENCIES.<\/li>\n<li>Take nutritional supplements as needed.\u00a0Find them under\u00a0NUTRIENT DEFICIENCIES.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>Recovery<\/strong>. You should begin to feel better within a week and notice more energy as inflammation subsides and the \u00a0absorbing cells that make up the surface lining of your small intestine are better able to function.<\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li>Intestinal lining cells are replaced every 5 days. The healing process is like sunburn where the damaged surface layer of skin sloughs off and is replaced with new normal cells.<\/li>\n<li>Leaky gut normally resolves in two month after starting a gluten free diet and brings about a big improvement in health. Improvement in intestinal permeability precedes morphometric recovery (cell appearance and structure) of the small intestine in celiac disease.<a href=\"#footnote_9_324\" id=\"identifier_9_324\" class=\"footnote-link footnote-identifier-link\" title=\"Cummins AG, Thompson FM, Butler RN, et al. Improvement in intestinal permeability precedes morphometric recovery of the small intestine in coeliac disease.&nbsp;Clinical Science. Apr 2001;100(4):379-86.\">9<\/a><\/li>\n<li>The intestinal lining may take up to a year to heal.\n\t\t\t<\/div><\/div><\/li>\n<\/ul>\n<ul class=\"cp_check green\" style=\"text-align: justify\">\n<li><em><span style=\"color: #800000\"><span class=\"dropcap\"><strong>2<\/strong><\/span><\/span><strong><span style=\"color: #800000\">\u00a0Reduce Inflammation. Foods to Eat and Foods Not to Eat:<\/span><\/strong><\/em><\/li>\n<\/ul>\n<p style=\"text-align: justify\">Because gluten is inflammatory, eliminate OTHER inflammatory foods from your diet to reduce an additive effect to gluten. At the same time, try to eat foods that reduce inflammation (anti-inflammatory).<\/p>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t<strong>Here Are Major Inflammatory Food Types That Reduce Healing<\/strong>:<\/p>\n<ul class=\"cp_bullet red\" style=\"text-align: justify\">\n<li><strong>Damaging Foods<\/strong>. In susceptible persons, includes corn, dairy (cow), and soy. Lactose, the sugar in any animal milk disrupts intestinal permeability causing leaky gut.<a href=\"#footnote_10_324\" id=\"identifier_10_324\" class=\"footnote-link footnote-identifier-link\" title=\"Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease.&nbsp;Journal of Gastroenterology and Hepatology. 2003;18:479-91.\">10<\/a><\/li>\n<li><strong>Allergenic Foods<\/strong>. Includes foods that trigger the immune sytem to produce IgE antibodies. Allergy testing is the usual way to discover these offending foods.<\/li>\n<li><strong>Shelf Stable Processed Foods.\u00a0<\/strong>Includes any that contain additives and preservatives. Look for them on the nutrition label of the box or package. Additives and preservatives also disrupt intestinal permeability causing leaky gut.<a href=\"#footnote_10_324\" id=\"identifier_11_324\" class=\"footnote-link footnote-identifier-link\" title=\"Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease.&nbsp;Journal of Gastroenterology and Hepatology. 2003;18:479-91.\">10<\/a><\/li>\n<li><strong>Fats.<\/strong>\u00a0Limit deep fried foods, trans-fats, saturated fats (animal fat\/butter), and EXCESSIVE omega-6 fatty acid oils like corn oil. Rancid fats, sodium caprate (a medium chain fat), and sucrose monester fatty acid (a food grade surfactant) induce significant disruption of the intestinal barrier that causes leaky gut.<a href=\"#footnote_10_324\" id=\"identifier_12_324\" class=\"footnote-link footnote-identifier-link\" title=\"Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease.&nbsp;Journal of Gastroenterology and Hepatology. 2003;18:479-91.\">10<\/a>.<\/li>\n<li><strong>Excessive Refined White Flours\u00a0<\/strong>(bran layer removed)<strong>.\u00a0<\/strong>Includes\u00a0products made from them such as cookies, bread, cakes, pies.\u00a0Bran contains the vitamins and minerals that metabolize grains and slows the otherwise rapid entry of sugar from their digestion into the bloodstream.\u00a0Also disrupt intestinal permeability causing leaky gut.<a href=\"#footnote_10_324\" id=\"identifier_13_324\" class=\"footnote-link footnote-identifier-link\" title=\"Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease.&nbsp;Journal of Gastroenterology and Hepatology. 2003;18:479-91.\">10<\/a><\/li>\n<li><strong>Refined Sugars.\u00a0<\/strong>\u00a0Includes white sugar, corn fructose and high fructose corn syrup.<\/li>\n<li><strong>Certain Spices<\/strong>. Includes paprika and cayenne pepper which disrupt intestinal permeability causing leaky gut.<a href=\"#footnote_10_324\" id=\"identifier_14_324\" class=\"footnote-link footnote-identifier-link\" title=\"Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease.&nbsp;Journal of Gastroenterology and Hepatology. 2003;18:479-91.\">10<\/a><\/li>\n<li><strong>Alcohol and Caffeine<\/strong>. Disrupt intestinal permeability causing leaky gut.<a href=\"#footnote_10_324\" id=\"identifier_15_324\" class=\"footnote-link footnote-identifier-link\" title=\"Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease.&nbsp;Journal of Gastroenterology and Hepatology. 2003;18:479-91.\">10<\/a>\n\t\t\t<\/div><\/div><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t<strong>Here Are Important Anti-Inflammatory Food Types to Promote Health<\/strong>:<\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li><strong>Fruits<\/strong>.\u00a0Contain ample amounts of vitamins, minerals and phytochemicals which are\u00a0naturally occuring components in plants that detoxify toxins, carcinogens (reducing the risk by 50%) and mutagens.<\/li>\n<li><strong>Non-Starchy Vegetables.<\/strong>\u00a0Support intestinal integrity and provide ample amounts of vitamins, minerals and phytochemicals. Includes green leafy vegetables such as lettuce and kale, also onion, broccoli, garlic, and others.<\/li>\n<li><strong>High Quality Complex Carbohydrates<\/strong>. Provide vitamins, minerals, and fiber while boosting serotonin levels to help you relax and feel calm. Includes whole grains, legumes, and root vegetables such as carrots, parsnips, sweet potatoes, turnips, red beets, and others.<\/li>\n<li><strong>Antioxidants<\/strong>. Protect the body from inflammatory oxidant molecules that continually occur and\u00a0help us handle stress and reduce irritability. Includes vitamin C-containing foods such as lemon, grapefruit, apricot, Brussels sprouts and strawberries, and others. Also, includes vitamin E-containing foods such as\u00a0nuts, seeds, avocado, olive oil, and others. Cocoa is good, too.<\/li>\n<li><strong>Omega-3 Fatty Acids<\/strong>. Balance opposing omega-6 fatty acids and bad fats. Fish sources includes tuna, salmon, cod, and others. Plants sources include flax, chia seeds, canola oil, and others.<\/li>\n<li><strong>Probiotics.\u00a0<\/strong>Supply normal microbes needed for colon health and health of the body such as these fermented foods: yogurt, kefir, and unpasteurized apple cider vinegar.<\/li>\n<li><strong>Prebiotics\/ High Fiber Foods<\/strong>. \u00a0Food with fiber keeps our population of colonic microbes healthy.<\/li>\n<li><strong>Protective Herbs and Spices<\/strong>. \u00a0See below #6 below for examples.\n\t\t\t<\/div><\/div><\/li>\n<\/ul>\n<ul class=\"cp_check green\" style=\"text-align: justify\">\n<li><em><span style=\"color: #800000\"><strong><span class=\"dropcap\">3<\/span>\u00a0Information Sheet You Can Take to Your Doctor or Other Health Professional:<\/strong><\/span><\/em><\/li>\n<\/ul>\n<p style=\"text-align: justify\">Click here.<\/p>\n<ul class=\"cp_check green\" style=\"text-align: justify\">\n<li><span style=\"color: #800000\"><strong><em><span class=\"dropcap\">4<\/span>\u00a0Manage Your Medications\u00a0Safely<\/em>:<\/strong><\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t\n<p style=\"text-align: justify\">Certain medications cause deficiencies of omega-3 fatty acids, selenium, thiamin (vitamin B1), vitamin B12 and niacin (vitamin B3) that predispose to adenocarinoma of the small intestine. \u00a0Ask your doctor or pharmacist about this possible adverse effect if you are taking any of the drugs listed below.\u00a0<strong>Do not stop prescribed medications without supervision.<\/strong><\/p>\n<p style=\"text-align: justify\">This is not a complete listing.<\/p>\n<p style=\"text-align: justify\"><strong>ANTACIDS \/ ULCER MEDICATIONS<\/strong><\/p>\n<ul class=\"cp_bullet blue\" style=\"text-align: justify\">\n<li>Pepcid\u00ae, Tagamet\u00ae, Zantac\u00ae deplete Vitamin B12.<\/li>\n<li>Magnesium and Aluminum Antacid preparations (Gaviscon\u00ae, Maalox\u00ae, Mylanta\u00ae) deplete Vitamin B12.<\/li>\n<li>Prevacid\u00ae, Prilosec\u00ae\u00a0deplete Vitamin B12.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>ANTI-DEPRESSANTS<\/strong><\/p>\n<ul class=\"cp_bullet blue\" style=\"text-align: justify\">\n<li>Adapin\u00ae, Aventyl\u00ae, Elavil\u00ae, Pamelor\u00ae, and others\u00a0deplete\u00a0Vitamin B12.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>ANTIBIOTICS\u00a0<\/strong>disrupt intestinal permeability which complicates celiac disease.<\/p>\n<ul class=\"cp_bullet blue\" style=\"text-align: justify\">\n<li>Gentomycin, Neomycin, Streptomycin, Cephalosporins, Penicillins\u00a0deplete\u00a0B Vitamins.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>ANTI-INFLAMMATORIES<\/strong>\u00a0disrupt intestinal permeability which complicates celiac disease.<\/p>\n<ul class=\"cp_bullet blue\" style=\"text-align: justify\">\n<li>Corticosteroids (Prednisone, Medrol\u00ae, Aristocort\u00ae, Decadron) deplete Selenium,\u00a0Vitamin B12.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>ANTICONVULSANTS<\/strong><\/p>\n<ul class=\"cp_bullet blue\" style=\"text-align: justify\">\n<li>Phenobarbital and Barbituates; and Dilantin\u00ae, Tegretol\u00ae, Mysoline\u00ae, Depakane\/Depacon\u00ae deplete Vitamin B12, Vitamin B1, Selenium.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>ANTIVIRAL AGENTS<\/strong><\/p>\n<ul class=\"cp_bullet blue\" style=\"text-align: justify\">\n<li>Zidovudine (Retrovir\u00ae, AZT and other related drugs) deplete Vitamin B12.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>CARDIOVASCULAR DRUGS<\/strong><\/p>\n<ul class=\"cp_bullet blue\" style=\"text-align: justify\">\n<li>Antihypertensives (Catapres\u00ae, Aldomet) deplete Vitamin B1.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>CHOLESTEROL DRUGS<\/strong><\/p>\n<ul class=\"cp_bullet blue\" style=\"text-align: justify\">\n<li>Colestid\u00ae and Questran\u00ae deplete\u00a0Vitamin B12.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>DIABETIC DRUGS\u00a0<\/strong><\/p>\n<ul class=\"cp_bullet blue\" style=\"text-align: justify\">\n<li>Metformin\u00ae depletes Vitamin B12.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>DIURETICS<\/strong><\/p>\n<ul class=\"cp_bullet blue\" style=\"text-align: justify\">\n<li>Loop Diuretics (Lasix\u00ae, Bumex\u00ae, Edecrin\u00ae) depletes Vitamin B1.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>FEMALE HORMONES<\/strong>\u00a0disrupt intestinal permeability which complicate celiac disease.<\/p>\n<ul class=\"cp_bullet blue\" style=\"text-align: justify\">\n<li>Oral Contraceptives (Norinyl\u00ae, Ortho-Novum\u00ae, Triphasil\u00ae, and others) deplete Vitamin B3, Selenium,\u00a0Vitamin B12.<\/li>\n<li>Oral Estrogen\/Hormone Replacement (Evista\u00ae, Prempro\u00ae, Premarin\u00ae, Estratab\u00ae and others) deplete \u00a0Vitamin B12.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>MAJOR TRANQUILIZERS<\/strong>\u00a0<strong>\u00a0<\/strong><\/p>\n<ul class=\"cp_bullet blue\" style=\"text-align: justify\">\n<li>Thorazine\u00ae, Mellaril\u00ae, Prolixin\u00ae, Serentil\u00ae and others\u00a0deplete Vitamin B12.\n\t\t\t<\/div><\/div><\/li>\n<\/ul>\n<ul class=\"cp_check green\" style=\"text-align: justify\">\n<li><em><span style=\"color: #800000\"><strong><span class=\"dropcap\">5<\/span>Nutritional Supplements To Help Correct Deficiencies:<\/strong><\/span><\/em><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t\n<ul class=\"cp_bullet orange\" style=\"text-align: justify\">\n<li>Multivitamin\/mineral combination once a day is useful to improve overall nutrient levels. This is a safe dose, but always check with your doctor to avoid interactions with medications.<\/li>\n<li>B-Vitamin Complex supplement to restore vitamin B1 and B3 as needed.<\/li>\n<li>Vitamin B12 as prescribed following blood test for status.<\/li>\n<li>Selenium as prescribed following blood test for status.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>Storage Note<\/strong>:\u00a0<em>Store container tightly sealed, away from heat, moisture and direct light to avoid loss of potency. That is, in a safe kitchen cabinet &#8211; not in the bathroom or on the kitchen table<\/em>.\n\t\t\t<\/div><\/div>\n<ul class=\"cp_check green\" style=\"text-align: justify\">\n<li><span style=\"color: #800000\"><em><strong><span class=\"dropcap\">6<\/span>Manage Natural Remedies:\u00a0<\/strong><\/em><\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t<strong>Hydration<\/strong>:<\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li>Eight glasses of water are recommended per day unless there is a contraindication such as kidney or heart disease. The Institute of Medicine recommends approximately 2.7 liters (91 ounces) of total water, from all beverages and foods, each day for women and 3.7 liters (125 ounces) daily of total water for men.<\/li>\n<li>If you are thirsty, drink water. Add fresh, squeezed lemon to water. Lemon is anti-inflammatory, alkalizing and provides vitamin C.<\/li>\n<li>Hydration Test: Urine should be pale yellow. Fingertips should be plump, without pruning but this may not be reliable when fingers are swollen with edema. Lips should be plump, without puckering. The feeling of thirst can be unreliable.<\/li>\n<li>What is wrong with soda, coffee, tea, and alcohol? These drinks are dehydrating, increase acid, and deplete nutrients.\n\t\t\t<\/div><\/div><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t<strong>Carminatives.\u00a0<\/strong>The following \u00a0anti-inflammatory\u00a0plant sources called carminitives help heal the digestive tract. They also tone the digestive muscles which improves peristalsis, thus aiding in the expulsion of gas from the stomach and intestine to relieve digestive colic and gastric discomfort.<\/p>\n<p style=\"text-align: justify\"><strong>Carminative Food Remedies<\/strong>:<\/p>\n<ul class=\"cp_bullet green\" style=\"text-align: justify\">\n<li>Raspberry.<\/li>\n<li>Carrot is also a cleansing digestive tonic.<\/li>\n<li>Grape is also bile stimulating and a cleansing remedy for sluggish digestion and laxative.<\/li>\n<li>Redbeets also stimulate and improve digestion and are easily digested.<\/li>\n<li>Cabbage also stimulates and improves digestion and is also a liver decongestant.<\/li>\n<li>Lettuce also stimulates and improves digestion and is also an alterative, meaning it improves the function of organs involved with the digestion and excretion of waste products to bring about a gradual change.<\/li>\n<li>Potatoes are antispasmodic (due to atropine like properties) and a liver remedy.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><strong>Carminative Herb Remedies:<\/strong><\/p>\n<ul class=\"cp_bullet green\">\n<li style=\"text-align: justify\">Sage is also a digestive, astringent, bile stimulant and energy tonic that heals the mucosa. \u00a0Drink as tea or use in cooking.<\/li>\n<li style=\"text-align: justify\">Chamomile, lemon balm, and fennel, (as a tea) also help relieve nervous tension.<\/li>\n<li style=\"text-align: justify\">Parsley also relieves indigestion.<\/li>\n<li style=\"text-align: justify\">Rosemary as a tea and in cooking also is a nervous system tonic for stress and fatigue, bile stimulant, and can relieve headaches and indigestion.<\/li>\n<li style=\"text-align: justify\">Thyme is also soothing remedy useful for stimulating digestion of rich, fatty foods.<\/li>\n<\/ul>\n<p><strong>Carminative Spice Remedies:<\/strong><\/p>\n<ul class=\"cp_bullet green\">\n<li>Cloves are also antispasmodic.<\/li>\n<li>Nutmeg is also useful for indigestion.<\/li>\n<li>Ginger.\n\t\t\t<\/div><\/div><\/li>\n<\/ul>\n<div class=\"box shadow\"><div class=\"box-inner-block\"><i class=\"tieicon-boxicon\"><\/i>\n\t\t\t<strong>Exercise Helps<\/strong>:<\/p>\n<p>Exercise improves circulation and rids the body of toxins.<\/p>\n<ul class=\"cp_bullet green\">\n<li>Walking is aerobic exercise that reconditions the whole body to improve stamina.\u00a0Read more about<a href=\"https:\/\/glutenfreeworks.com\/health\/2014\/07\/08\/fitness-guide\/\">\u00a0Exercise and Fitness<\/a>.<\/li>\n<li>Weight training builds muscle.\u00a0Read more about\u00a0<a href=\"https:\/\/glutenfreeworks.com\/health\/2014\/07\/08\/fitness-guide\/\">Exercise and Fitness<\/a>.<\/li>\n<li>Stretching improves flexibilty.\u00a0Read more about\u00a0<a href=\"https:\/\/glutenfreeworks.com\/health\/2014\/07\/08\/fitness-guide\/\">Exercise and Fitness<\/a>.<\/li>\n<\/ul>\n<p><strong>Note<\/strong>: Exercise is important, but the amount and type of exercise undertaken depends on your health. Your first priority is to heal. \n\t\t\t<\/div><\/div>\n<h2>What Do Medical Research Studies Tell About Adenocarcinoma of Small Intestine?<\/h2>\n<h4><strong>RESEARCH STUDY SUMMARIES<\/strong><\/h4>\n<p style=\"text-align: justify\"><strong>\u201cUntreated celiac disease in a patient with dermatitis herpetiformis leading to a small bowel carcinoma.\u201d<\/strong> This case report describes a 69-year-old man with a history of dermatitis herpetiformis who presented to a tertiary center for a second opinion for a suspected gastric motility disorder. This diagnosis was based on the combination of upper abdominal pain for over 2 years and repetitive episodes of vomiting. Immediately after referral, celiac disease was diagnosed and a gluten-free diet was started. In the next half year of follow-up, additional anemia and weight loss developed and eventually a small bowel adenocarcinoma was diagnosed. Revision of a small bowel follow-through, which had been performed 2 years earlier, showed that the tube had been positioned just distal from the process. Therefore, this diagnosis had not been made at that time. Unfortunately, curative therapy was not possible and the patient died a few months later. In conclusion, all patients with dermatitis herpetiformis have a gluten-sensitive enteropathy and should be treated with a gluten-free diet. Next to this it is important to notice that patients with celiac disease have an increased risk of developing a small bowel malignancy. Unexplained upper abdominal pain, weight loss and anemia should lead to additional investigations to exclude a small bowel malignancy in these patients. At last, the diagnosis of a small bowel carcinoma is difficult.<a href=\"#footnote_11_324\" id=\"identifier_16_324\" class=\"footnote-link footnote-identifier-link\" title=\"Derikx MH, Bisseling TM. Untreated celiac disease in a patient with dermatitis herpetiformis leading to a small bowel carcinoma. Case Rep Gastroenterol. 2012 Jan;6(1):20-5. doi: 10.1159\/000336066.\">11<\/a><\/p>\n<p style=\"text-align: justify\"><strong>\u201cCoeliac disease and malignancies.&#8221;<\/strong> This study investigating the prevalence of cancer in celiac disease found that compared with the general population, patients with coeliac disease\u00a0have an increased risk of developing enteropathy-associated T-cell lymphoma (EATCL), esophageal and pharyngeal squamous carcinomas and small intestinal adenocarcinomas. The prevalence of histologically confirmed celiac disease in Edinburgh and the Lothians in 1979 was 61 per 100,000. The National Health Service Central Records of all 653 subjects registered at that time have been flagged, allowing us to analyse mortality in celiac disease. At a mean of 13.5 years, mortality overall was 1.9-fold that of the general population (115 deaths observed. 61.8 expected; p &lt; 0.0001). For both sexes the early mortality was much greater than expected, but the excess steadily diminished with time from diagnosis.<a href=\"#footnote_12_324\" id=\"identifier_17_324\" class=\"footnote-link footnote-identifier-link\" title=\"Ferguson A, Kingstone K. Coeliac disease and malignancies. Acta Paediatr Suppl. 1996 May;412:78-81.\">12<\/a><\/p>\n<h4><strong>CASE REPORT SUMMARIES<\/strong><\/h4>\n<p style=\"text-align: justify\"><strong>\u201cSmall Bowel Adenocarcinoma Complicating Coeliac Disease: A Report of Three Cases and the Literature Review.\u201d<\/strong> This case report describes three cases of a small bowel adenocarcinoma in the setting of celiac disease in order to underline the epidemiological features, clinicopathological findings, and therapeutic approaches of this entity based on a review of the literature. The three patients underwent a surgical treatment followed by adjuvant chemotherapy based on capecitabine\/oxaliplatin regimen, and they have well recovered.<a href=\"#footnote_13_324\" id=\"identifier_18_324\" class=\"footnote-link footnote-identifier-link\" title=\"Benhammane H,,*&nbsp;El M&rsquo;rabet FZ,&nbsp;Serhouchni KI,&nbsp;El yousfi M,&nbsp;Charif I,&nbsp;Toughray I, et al. Small Bowel Adenocarcinoma Complicating Coeliac Disease: A Report of Three Cases and the Literature Review. Case Rep Oncol Med. 2012; 2012: 935183. Published online 2012 December 1. doi: 10.1155\/2012\/935183\">13<\/a><\/p>\n<p style=\"text-align: justify\"><strong>&#8220;Laparoscopic treatment of mucinous adenocarcinoma of jejunum associated with celiac disease.&#8221;<\/strong> This case report describes a unique case of jejunal mucinous adenocarcinoma in which a concomitant celiac disease has been histologically recognized. A 49-year-old man presented with recurrent melena, nausea, vomiting and anemia. A stenosis of the jejunum was documented by means of CT scan and video capsule enteroscopy. A laparoscopy was scheduled. A tumor, found in the first jejunal loop, was removed by laparoscopic surgery. Histopathology revealed a rare mucinous adenocarcinoma associated with epithelial changes secondary to celiac disease. Physicians state, &#8220;Although small bowel tumors are rare entity, in patients with celiac disease complaining of symptoms related to altered intestinal transit or occult bleeding, an appropriate work-up should be planned for diagnosis. Laparoscopic surgery is often essential for the diagnosis and treatment.&#8221;<a href=\"#footnote_14_324\" id=\"identifier_19_324\" class=\"footnote-link footnote-identifier-link\" title=\"Vecchio R, Marchese S, Gangemi P, Alongi G, Ferla F, Spataro C, Intagliata E. &nbsp;Case report. G Chir. 2012 Apr;33(4):126-8.\">14<\/a><\/p>\n<p style=\"text-align: justify\"><strong>&#8220;Duodeno-jejunal adenocarcinoma as a first presentation of coeliac disease.&#8221;<\/strong>\u00a0This case report describes two patients whose initial presentation was adenocarcinoma of the small bowel, but who were subsequently found to have celiac disease after Whipple&#8217;s resection. The diagnosis was made early in the postoperative period in the first patient after close histological examination of the tumour-free mucosal margins. This patient was placed on a gluten-free diet and had an uncomplicated postoperative recovery with rapid weight gain.<\/p>\n<p style=\"text-align: justify\">Diagnosis and dietary intervention in the second patient was very delayed and resulted in the development of severe malabsorption and weight loss. This illustrates the importance of ruling out celiac disease prior to surgery in patients with small intestinal malignancies.<a href=\"#footnote_15_324\" id=\"identifier_20_324\" class=\"footnote-link footnote-identifier-link\" title=\"MacGowan D J,&nbsp; Hourihane D O,&nbsp; Tanner W A, and&nbsp; O&rsquo;Morain C. Duodeno-jejunal adenocarcinoma as a first presentation of coeliac disease. J Clin Pathol. 1996 July; 49(7): 602&ndash;604.\">15<\/a><\/p>\n<p style=\"text-align: justify\"><strong>\u201cBody content of selenium in coeliac disease.\u201d<\/strong> This study investigating selenium concentations in whole blood, plasma, and leukocytes of patients with biopsy confirmed celiac disease, who were clinically well and receiving gluten free diet, demonstrated significantly lower concentrations than controls, probably indicating a decrease in the body content of selenium. A high incidence of malignancy in celiac disease has been reported. As a protective role for selenium against cancer has been postulated, the importance of this unexpected observation of lowered tissue concentrations of selenium requires further investigation.<a href=\"#footnote_16_324\" id=\"identifier_21_324\" class=\"footnote-link footnote-identifier-link\" title=\"Hinks LJ, Inwards KD, Lloyd B, Clayton BE. Body content of selenium in coeliac disease. British Medical Journal. Jun 23, 1984;288(6434):1862-3.\">16<\/a><\/p>\n<p style=\"text-align: justify\">\n<ol class=\"footnotes\"><li id=\"footnote_1_324\" class=\"footnote\">Benhammane H,\u00a0El M&#8217;rabet FZ,\u00a0Serhouchni KI,\u00a0El yousfi M,\u00a0Charif I,\u00a0Toughray I, et al. Small Bowel Adenocarcinoma Complicating Coeliac Disease: A Report of Three Cases and the Literature Review.\u00a0<\/span><em style=\"line-height: 1.5em\">Case Rep Oncol Med<\/em><span style=\"line-height: 1.5em\">. 2012; 2012: 935183. Published online 2012 December 1. doi: 10.1155\/2012\/935183<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_1_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_2_324\" class=\"footnote\">Ramachandran I, Sinha R, Rajesh A, Verma R. Multidetector row CT of small bowel tumors. \u00a0<em>Clinical Radiology<\/em>. 2007; 62:607-614.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_2_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_3_324\" class=\"footnote\">Benhammane H,\u00a0El M&#8217;rabet FZ,\u00a0Serhouchni KI,\u00a0El yousfi M,\u00a0Charif I,\u00a0Toughray I, et al. Small Bowel Adenocarcinoma Complicating Coeliac Disease: A Report of Three Cases and the Literature Review. <em>Case Rep Oncol Med<\/em>. 2012; 2012: 935183. Published online 2012 December 1. doi: 10.1155\/2012\/935183<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_3_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_4_324\" class=\"footnote\">Ferguson A, Kingstone K. Coeliac disease and malignancies. <em>Acta Paediatr Suppl<\/em>. 1996 May;412:78-81.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_4_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_5_324\" class=\"footnote\">Rampertab SD, Fleischauer A, Neugut AI, Green PH. Risk of duodenal adenoma in celiac disease. <em>Scandanavian Journal of Gastroentorology<\/em>. Aug 2003;38(8):831-3.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_5_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_6_324\" class=\"footnote\">Ramachandran I, Sinha R, Rajesh A, Verma R. Multidetector row CT of small bowel tumors. \u00a0<\/span><em style=\"text-align: justify;line-height: 1.5em\">Clinical Radiology<\/em><span style=\"text-align: justify;line-height: 1.5em\">. 2007; 62:607-614.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_6_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_7_324\" class=\"footnote\">Hinks LJ, Inwards KD, Lloyd B, Clayton BE. Body content of selenium in coeliac disease.\u00a0<i>British Medical Journal.<\/i>\u00a0Jun 23, 1984;288(6434):1862-3.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_7_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_8_324\" class=\"footnote\">Green PH, Fleischauer AT, Bhagat G, Goyal R, Jabri B, Neugut AI. Risk of malignancy in patients with celiac disease. <em>American Journal of Medicine<\/em>. Aug 15, 2003;115(3):191-5.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_8_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_9_324\" class=\"footnote\">Cummins AG, Thompson FM, Butler RN, et al. Improvement in intestinal permeability precedes morphometric recovery of the small intestine in coeliac disease.\u00a0<em>Clinical Science<\/em>. Apr 2001;100(4):379-86.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_9_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_10_324\" class=\"footnote\">Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease.\u00a0<em>Journal of Gastroenterology and Hepatology<\/em>. 2003;18:479-91.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_10_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_11_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_12_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_13_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_14_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_15_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_11_324\" class=\"footnote\">Derikx MH, Bisseling TM. Untreated celiac disease in a patient with dermatitis herpetiformis leading to a small bowel carcinoma. <em>Case Rep Gastroenterol<\/em>. 2012 Jan;6(1):20-5. doi: 10.1159\/000336066.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_16_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_12_324\" class=\"footnote\">Ferguson A, Kingstone K. Coeliac disease and malignancies. <em>Acta Paediatr Suppl.<\/em> 1996 May;412:78-81.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_17_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_13_324\" class=\"footnote\">Benhammane H,,*\u00a0El M&#8217;rabet FZ,\u00a0Serhouchni KI,\u00a0El yousfi M,\u00a0Charif I,\u00a0Toughray I, et al. Small Bowel Adenocarcinoma Complicating Coeliac Disease: A Report of Three Cases and the Literature Review. <em>Case Rep Oncol Me<\/em>d. 2012; 2012: 935183. Published online 2012 December 1. doi: 10.1155\/2012\/935183<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_18_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_14_324\" class=\"footnote\">Vecchio R, Marchese S, Gangemi P, Alongi G, Ferla F, Spataro C, Intagliata E. \u00a0Case report. <em>G Chir<\/em>. 2012 Apr;33(4):126-8.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_19_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_15_324\" class=\"footnote\"> MacGowan D J,\u00a0 Hourihane D O,\u00a0 Tanner W A, and\u00a0 O&#8217;Morain C. Duodeno-jejunal adenocarcinoma as a first presentation of coeliac disease. <i>J Clin Pathol<\/i>. 1996 July; 49(7): 602\u2013604.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_20_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_16_324\" class=\"footnote\">Hinks LJ, Inwards KD, Lloyd B, Clayton BE. Body content of selenium in coeliac disease. <em>British Medical Journal.<\/em> Jun 23, 1984;288(6434):1862-3.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_21_324\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><\/ol>","protected":false},"excerpt":{"rendered":"<p>What Is Adenocarcinoma Of Small Intestine? Adenocarcinomas are malignant tumors, or cancer, of the small bowel arising out of glandular tissue. They fall in the category of rare neoplasm, comprising only 3% of all gastrointestinal malignancies. Primary adenocarcinoma is the most common histological (cell) subtype constituting 35\u201350% of cases.1\u00a0 Q: What does adenocarcinoma look like? &#8230;<\/p>\n","protected":false},"author":29,"featured_media":6009,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[4,160,783,119,124,159,65,127,107,143],"tags":[813,300,1937,558,116,776,829,1914,1919,1936,1895,1385,981,1905,1925,434],"class_list":["post-324","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-conditions-2","category-antioxidant","category-complications-health-conditions-2","category-omega-3-fatty-acids","category-selenium","category-small-intestine","category-digestive","category-thiamin","category-vitamin-b12","category-niacin","tag-adenocarcinoma-of-small-intestine","tag-anemia","tag-antioxidant","tag-cancer","tag-complications","tag-health-conditions","tag-occult-gastrointestinal-bleeding","tag-omega-3-fatty-acids","tag-selenium","tag-small-intestine","tag-digestive","tag-upper-abdominal-pain","tag-vitamin-b1-thiamin","tag-vitamin-b12","tag-niacin","tag-weight-loss"],"_links":{"self":[{"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/posts\/324","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/users\/29"}],"replies":[{"embeddable":true,"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/comments?post=324"}],"version-history":[{"count":24,"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/posts\/324\/revisions"}],"predecessor-version":[{"id":18794,"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/posts\/324\/revisions\/18794"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/media\/6009"}],"wp:attachment":[{"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/media?parent=324"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/categories?post=324"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/glutenfreeworks.com\/health\/wp-json\/wp\/v2\/tags?post=324"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}