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Tag Archives: autoantibodies

Anti-tissue Transglutaminase Antibodies (tTG) Present In Blood

What Are Anti-tissue Transglutaminase Antibodies? Anti-tissue transglutaminase antibodies (anti-tTG) are connective tissue autoantibodies and can be detected in blood samples from affected persons who are reacting to gluten in the diet. Autoantibodies are abnormal because they attack the body’s own ...

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Autoimmune Polyglandular Syndromes 

What Are Autoimmune Polyglandular Syndromes? Autoimmune polyglandular syndromes (APS) are rare clusterings of two or more endocrine and non-endocrine autoimmune disorders in the same affected person. Polyglandular is somewhat of a misnomer since many of the manifestations of the diseases ...

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Chronic Bullous Dermatosis of Childhood or Linear IgA Dermatosis

What Is Chronic Bullous Dermatosis Of Childhood? Chronic bullous dermatosis of childhood, also termed linear IgA dermatosis, is the most common acquired autoimmune blistering disorder of childhood and is characterized by itchy, urticated papules and plaques as well as polycyclic lesions (merged ...

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Diabetes Mellitus, Type I

What Is Type I Diabetes Mellitus? Type 1 diabetes mellitus (T1DM), also termed type 1A, is an inherited autoimmune disorder in which anti-islet autoantibodies destroy the islet cells of the pancreas that secrete insulin hormone. Type 1 diabetes mellitus was formerly ...

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Multiple Sclerosis: definition

An autoimmune, chronic slowly progressive demyelinating (damage to nerve fibers) disease of the central nervous system characterized by multiple and varied neurologic symptoms and signs such as numbness, muscle weakness and visual disturbances, usually with exacerbations and remissions. Click for full ...

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Keratoconjunctivitis Sicca: definition

An autoimmune disorder causing chronic  dryness with inflammation of the conjunctiva and cornea of both eyes due to tear abnormality. Click for full description.

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Juvenile Autoimmune Thyroid Disease: definition

An autoimmune thyroid disease in children characterized by abnormal circulating thyroid hormone levels. Click for full description.

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