Tag Archives: Associated Disorders

What Is Hypokalemic Rhabdomyolysis? Hypokalemic rhabdomyolysis is an acute and sometimes fatal disease due to its rapid progression of muscle destruction when untreated. It is characterized by the accumulation of by-products of skeletal muscle destruction in the renal (kidney) tubules ...

What Is Pityriasis Rubra Pilaris? Pityriasis rubra pilaris (PRP) is a chronic generalized exfoliative dermatitis (sloughing skin) characterized by erythema (redness), scaling, dilated plugged hair follicles, and keratoderma (thickened skin) of the hands and feet that is often associated with ...

What Is Acquired Ichthyosis? Acquired ichthyosis is an uncommon, nonhereditary cutaneous disorder characterized by dry, rough skin with prominent symmetrical scaling that involves significant portions of the body. Most microscopic studies of acquired ichthyosis exhibit hyperkeratosis (thickened skin) with a ...

What Is Erythema Nodosum? Erythema nodosum is an inflammatory disorder involving the deep dermis layer of skin and subcutaneous fat septa that underlies the skin. It is characterized by eruptions of recurrent or persistent multiple painful, red nodules under the skin that ...

What Is Cutaneous Vasculitis? Cutaneous vasculitis is a vascular disease of small blood vessels serving the skin that is characterized by segmental (spotty) inflammation of affected vessel walls resulting in their necrosis (destruction). Scarring is seen in the affected skin ...

What Is IgA Deficiency? IgA deficiency (IgAD) is an immunodeficiency disease characterized by lack of immunoglobulin A type antibody production, called IgA antibody, with no detectable levels in blood or secretions. Q: What is an IgA antibody? A: IgA is ...

What Is Common Variable Immunodeficiency? Common variable immunodeficiency (CVID) is a primary antibody deficiency disease characterized by the onset of recurrent bacterial infections resulting from markedly decreased immunoglobulin antibody production and antibody levels. Q: What causes common variable immunodeficiency? A: Common variable ...

What Are Autoimmune Disorders? Autoimmune disorders refer to those conditions that involve an abnormal attack on the body’s own tissues perpetuated by the production of autoantibodies directed against self. Q: What happens when autoantibodies attack the body’s own tissues? A: ...

What Is Allergic Rhinitis? Allergic rhinitis is an immune disorder characterized by inflammation of the nasal mucosa by an IgE antibody reaction to an allergen. An allergen is something that triggers an allergic immune response. Q: What is the immune ...

What Is Primary Hyperparathyroidism? Primary hyperparathyroidism is a parathyroid disorder characterized by excessive secretion of parathyroid hormone by one or more parathyroid glands for more than 6 months. In primary hyperparathyroidism, blood calcium levels are high while phosphorus levels are ...

What Is Pancreatic Insufficiency? Pancreatic insufficiency is a disorder characterized by insufficient exocrine production of pancreatic enzymes for normal digestion of fats, proteins, and carbohydrates that results in maldigestion of these foodstuffs. Pancreatic insufficiency also causes malabsorption of the fat-soluble ...

What Are Gastro-Intestinal Complications Of Type 1 Diabetes? Gastrointestinal complications of type I diabetes mellitus are functional or organic changes that result from diabetes affecting every organ of the gastrointestinal tract. Q: How do gastrointestinal tract complications affect diabetes? A: Impaired ...

What Is Diabetic Instability? Diabetic instability, also called brittle diabetes, is poor control of blood sugar characterized by frequent rise (hyperglycemia) and fall (hypoglycemia). These fluctuations can be life-threatening and cause unnecessary complications. Q: What are complications in diabetes? A: Complications ...

What Is Type I Diabetes Mellitus? Type 1 diabetes mellitus (T1DM), also termed type 1A, is an inherited autoimmune disorder in which anti-islet autoantibodies destroy the islet cells of the pancreas that secrete insulin hormone. Type 1 diabetes mellitus was formerly ...

What Is Hepatic Granulomatous Disease? Hepatic granulomatous disease is an infiltrative chronic liver disorder characterized by growth of small granulomas. Rather than being a final diagnosis, the presence of hepatic granulomas entails the need for further investigations towards identifying the ...