Tag Archives: Research

Research Study on Genetic Testing Looking for Survey Participants

Gluten Free Works Jennifer Harris

Columbia University Celiac Disease Center

The Celiac Disease Center at Columbia University invites you to participate in a research study looking at individuals’ knowledge of genetic testing of celiac disease and their potential concerns with such testing.  The goal of this study is to increase understanding of the factors associated with making an informed decision regarding such testing and to better provide the necessary information to make such a decision.

A brief survey has been developed to address some of these factors.  The survey only takes five minutes to complete, it is anonymous, and no identifying information is collected. 
 
If you or a family member has celiac disease or gluten sensitivity, Read More »

Researchers Develop A Faster Way To Diagnose Celiac Disease

John Libonati Gluten Free Works

The following article was written by Erika Gebel and reprinted by permision from Chemical and Engineering News.

Celiac Disease Gluten Sensitivity Test

Celiac Disease and Gluten Sensitivity Often Go Undiagnosed

Judging by their symptoms, people with celiac disease could have food poisoning, depression, or iron deficiency. As a result, doctors often have trouble diagnosing the serious immune disorder. To develop a better test for the disease, researchers have made a device that can detect nanograms of gluten antibodies, the hallmarks of celiac disease, in human Read More »

Study Finds Gluten Causes Digestive Symptoms and Fatigue in People Without Celiac Disease

irritable bowel glutenIn the first double blind randomized placebo-controlled study of gluten and symptoms in people without celiac disease, researchers from Australia have confirmed that gluten is a trigger of digestive symptoms and fatigue. They concede that “non-celiac gluten intolerance” may exist.

 

The researchers challenged and re-challenged people with IBS in whom celiac disease had been excluded whose symptoms were controlled on a gluten-free diet. These individuals were randomized to gluten-free diet with daily supplements of muffins and bread with a standard amount of gluten added or not added. Both the patients and the Read More »

Researchers Seeking Adults with Celiac Disease

Adults that have been diagnosed with Celiac Disease are being sought to participate in a study to identify factors associated with the development of Celiac Disease.  The goal of the study is to find the genes that may predispose individuals to develop this autoimmune disease.  Adults eligible to participate in this study must have been diagnosed with Celiac Disease through a small intestinal biopsy. Spouses may also be eligible to participate.

Participants will be asked to provide a blood sample, complete a questionnaire, and provide medical records regarding their diagnosis. There is no cost to Read More »

New Study Will Test Theory That Enzyme Contributes to Autism

The debate rages on both the causes and “cures” for autism. There is the mercury-vaccination contingent, the gluten-free, casein-free diet supporters, those that believe genetics play a role, and the list goes on. There may very well be multiple etiologies for this developmental disorder, and research continues throughout the world to determine, definitively and finally, what that is.

One of the newest clinical trials is just beginning across the country, at fifteen institutions, including the University of California at San Francisco. Read More »

MEDICAL RESEARCH: Vitamin D Deficiency is Associated with Insulin Resistance and ß cell Dysfunction

 

Editor’s note:

In the following medical research study, healthy participants were enrolled to examine the effects of vitamin D on insulin production and use in the body. This research shows that:

1) Vitamin D plays an important role in insulin sensitivity in the body, and deficiency of vitamin D hampers production of insulin hormone by beta cells in the pancreas.

2) People with vitamin D deficiency are at risk for developing type 2 diabetes mellitus. Type 2 diabetes mellitus is characterized by lack of insulin sensitivity in body tissues and inadequate production of insulin hormone in the pancreas. Read More »

Copper Malabsorption in Untreated Celiac Disease Common

 

Editor’s note:  

In this study, researchers investigating the absorption of copper in untreated patients who had damage to their duodenum found anemia in 3 out of 10 of these patients that was due to copper deficiency.  They gave all the study subjects a solution of copper to drink that was equal to a daily dose then tested their blood level.  Read More »

Gut Microflora Associated Characteristics in Children with Celiac Disease

Editor’s note: This important study demonstrated that short chain fatty acid (SCFA) levels in stool samples were abnormal in participating children with celiac disease, with and without treatment with gluten-free diet. SCFAs are healthy energy byproducts produced by microflora (beneficial organisms) in the colon during fermentation of undigested carbohydrates arriving from the small intestine. SCFAs nourish the colonocytes, cells that line the colon, to maintain normal function. They also help absorb salts and water from stool.  

“Gut Microflora Associated Characteristics in Children with Celiac Disease”

Tjellström B, et. al.

Microbiology and Tumour Biology Center, Karolinska Institute, Stockholm, Sweden.

Am J Gastroenterol. 2005 Dec;100(12):2784-8.

 

Background and aim: The aim of the study was to investigate the Read More »

MEDICAL RESEARCH: Vitamin D Necessary for Preserving Cognitive Function

 

Editor’s note: Promising research published January 8, 2007 shows that adequate levels of vitamin D in the elderly are important to maintain cognitive function or thinking skills that include use of language, awareness, social skills, math ability, memory, reasoning, judgment, intellect, learning, and imagination. This study is called a retrospective review because the researchers did not actually examine anyone. Instead they reviewed data from records of 32 older adults who had been examined for memory Read More »

MEDICAL RESEARCH: “Pediatric case series evaluating a standardized Candida albicans skin test prod

 

 Editors’ note: This study investigating the value and safety of Candin for clinical use in children demonstrated effectiveness and safety.  Candin is a reagent or skin test for sensitivity to Candida albicans, a yeast microorganism that can cause infection.  The study recommends using Candin in combination with other reagents in infants with anergy to see if they react to antigens other than Candida albicans.  Anergy is described in Taber’s Cyclopedic Medical Dictionary as the impaired or absent ability to react to common antigens administered through skin testing. Antigens are markers on the surface of cells that stimulate production of antibodies.  In this study, Candin was tested at the same time as a skin test for tuberculosis (purified protein derivative tuberculosis) for comparison of results. Read More »

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