Autoimmune Disorders

This category comprises autoimmune disorders caused by an abnormal immune system attack against the body’s own tissue(s).

Almost half of autoimmune disorders occur with other diseases. Some are organ specific like autoimmune thyroid disease which attacks the thyroid gland, whereas others affect multiple organs and/or are associated with systemic manifestations, such as systemic lupus erythematosus.

Addison’s Disease (Primary)

What Is Primary Addison’s Disease? Addison’s disease is an autoimmune destruction of the adrenal glands by autoantibodies that target the adrenal cortex, or outer part of these glands, and is characterized by a slow progressive failure of the adrenal glands ...

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Alopecia Areata

What Is Alopecia Areata? Alopecia areata is an autoimmune attack on hair follicles characterized by sudden hair loss involving scalp or beard, although any hairy area may be affected. Areas of hair loss have a patchy pattern with sharply defined ...

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Anti-Endomysium Antibodies (EMA) Present In Blood

What Are Anti-Endomysium Antibodies? Anti-endomysium antibodies (EmA) are connective tissue autoantibodies produced in persons who have inherited the genes for celiac disease, an autoimmune disease, and are reacting to gluten in their diet. Autoantibodies are abnormal in that they attack ...

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Anti-tissue Transglutaminase Antibodies (tTG) Present In Blood

What Are Anti-tissue Transglutaminase Antibodies? Anti-tissue transglutaminase antibodies (anti-tTG) are connective tissue autoantibodies and can be detected in blood samples from affected persons who are reacting to gluten in the diet. Autoantibodies are abnormal because they attack the body’s own ...

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Arthritis, Juvenile Idiopathic

What Is Juvenile Idiopathic Arthritis? Juvenile idiopathic arthritis (JIA) is a rheumatic disorder characterized by chronic, inflammatory disease of large and small synovial joints and other organs in children under age 16 years. Growth and development may be impaired in ...

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Autism and Learning Disabilities

What Is Autism and Learning Disabilities? Autism and learning disabilities constititute a non-progressive psychiatric syndrome appearing in childhood characterized by withdrawal from communication with others often accompanied by repetitive or primitive behaviors. Primary gastrointestinal pathology may play an important role ...

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Autoimmune Cholangitis

What Is Autoimmune Cholangitis? Autoimmune cholangitis is a rare inflammatory self-targeted disease of the biliary tract produced by high levels of immunoglobulin G (IgG) antibodies and antinuclear antibodies (ANA). Autoimmune cholangitis is characterized by progressive inflammation and scarring that leads to ...

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Autoimmune Disorders In Celiac Disease

What Are Autoimmune Disorders? Autoimmune disorders refer to those conditions that involve an abnormal immune attack on the body’s own tissues perpetuated by the production of autoantibodies directed against the body, or “self.” Auto means self. Q: Why does the ...

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Autoimmune Disorders In Dermatitis Herpetiformis

What Are Autoimmune Disorders? Autoimmune disorders refer to those conditions that involve an abnormal attack on the body’s own tissues perpetuated by the production of autoantibodies directed against self. Q: What happens when autoantibodies attack the body’s own tissues? A: ...

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Autoimmune Hepatitis

  What Is Autoimmune Hepatitis? Autoimmune hepatitis is an autoimmune attack against liver cells that is characterized by inflammation and results in chronic liver disease which includes low blood albumin and cirrhosis. Autoimmune hepatitis is diagnosed by detection of autoantibodies ...

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Autoimmune Polyglandular Syndromes 

What Are Autoimmune Polyglandular Syndromes? Autoimmune polyglandular syndromes (APS) are rare clusterings of two or more endocrine and non-endocrine autoimmune disorders in the same affected person. Polyglandular is somewhat of a misnomer since many of the manifestations of the diseases ...

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Chronic Bullous Dermatosis of Childhood or Linear IgA Dermatosis

What Is Chronic Bullous Dermatosis Of Childhood? Chronic bullous dermatosis of childhood, also termed linear IgA dermatosis, is the most common acquired autoimmune blistering disorder of childhood and is characterized by itchy, urticated papules and plaques as well as polycyclic lesions (merged ...

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Dermatitis Herpetiformis In Childhood

What Is Dermatitis Herpetiformis In Childhood? Dermatitis herpetiformis in childhood is an inflammatory skin manifestation of celiac disease in which immunoglobulin A (IgA) autoantibodies target components of the skin, leading to blister formation caused by ingestion of gluten in the diet.   Dermatitis ...

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Dermatitis Herpetiformis or Duhring’s Disease

What Is Dermatitis Herpetiformis? Dermatitis herpetiformis (DH) is an autoimmune extremely itchy, painful bullous skin rash (blistering eruptions) arising from the underlying dermis layer of skin as a consequence of gluten sensitivity. Dermatitis herpetiformis is characterized by multiple intensely itchy, ...

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Dermatomyositis

What Is Dermatomyositis? Dermatomyositis is a rare autoimmune systemic disease of the connective tissue that is characterized by inflammatory and debilitating degenerative changes in the muscles and in the skin.  Dermatomyositis results in symmetric, proximal muscle weakness of limbs (upper arms and ...

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