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System – Immune

This category comprises disorders of the immune system that cause damage to tissues and/or impairment of its protective function against invading organisms. The immune system includes proteins such as interferons, chemicals such as histamine, white blood cells including phagocytes and leukocytes, and immunoglobulins (antibodies).

Abscess Formation Causing Lung Cavities

What Is Abscess Formation Causing Lung Cavities? Abscess formation and subsequent lung cavities that develop from necrosis (death) of affected lung tissue constitute severe life-threatening respiratory disease  of the lung. Q: What is the difference between lung abscess and lung ...

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Allergic Rhinitis

What Is Allergic Rhinitis? Allergic rhinitis is an immune disorder characterized by inflammation of the nasal mucosa by an IgE antibody reaction to an allergen. An allergen is something that triggers an allergic immune response. Q: What is the immune ...

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Anti-Endomysium Antibodies (EMA) Present In Blood

What Are Anti-Endomysium Antibodies? Anti-endomysium antibodies (EmA) are connective tissue autoantibodies produced in persons who have inherited the genes for celiac disease, an autoimmune disease, and are reacting to gluten in their diet. Autoantibodies are abnormal in that they attack ...

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Anti-tissue Transglutaminase Antibodies (tTG) Present In Blood

What Are Anti-tissue Transglutaminase Antibodies? Anti-tissue transglutaminase antibodies (anti-tTG) are connective tissue autoantibodies and can be detected in blood samples from affected persons who are reacting to gluten in the diet. Autoantibodies are abnormal because they attack the body’s own ...

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Antiphospholipid Syndrome

What Is Antiphospholipid Syndrome? Antiphospholipid syndrome (APS) is an autoimmune disease and a blood clotting disorder characterized by these clinical and laboratory criteria: Clinical criteria – recurrent vascular thrombosis (clots in veins/arteries) from hypercoagulability (abnormal excessive clotting) and/or recurrent complications of ...

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Asthma

What Is Asthma? Asthma is a chronic immune respiratory condition characterized by narrowing and inflammation of the lung airways (large bronchi, bronchial tubes and small bronchioles) in response to an allergen as the trigger or stimulus. As such, asthma occurs ...

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Autoimmune Disorders In Celiac Disease

What Are Autoimmune Disorders? Autoimmune disorders refer to those conditions that involve an abnormal immune attack on the body’s own tissues perpetuated by the production of autoantibodies directed against the body, or “self.” Auto means self. Q: Why does the ...

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Autoimmune Disorders In Dermatitis Herpetiformis

What Are Autoimmune Disorders? Autoimmune disorders refer to those conditions that involve an abnormal attack on the body’s own tissues perpetuated by the production of autoantibodies directed against self. Q: What happens when autoantibodies attack the body’s own tissues? A: ...

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Autoimmune Polyglandular Syndromes 

What Are Autoimmune Polyglandular Syndromes? Autoimmune polyglandular syndromes (APS) are rare clusterings of two or more endocrine and non-endocrine autoimmune disorders in the same affected person. Polyglandular is somewhat of a misnomer since many of the manifestations of the diseases ...

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Common Variable Immunodeficiency 

What Is Common Variable Immunodeficiency? Common variable immunodeficiency (CVID) is a primary antibody deficiency disease characterized by the onset of recurrent bacterial infections resulting from markedly decreased immunoglobulin antibody production and antibody levels. Q: What causes common variable immunodeficiency? A: Common variable ...

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Diabetes Mellitus, Type I

What Is Type I Diabetes Mellitus? Type 1 diabetes mellitus (T1DM), also termed type 1A, is an inherited autoimmune disorder in which anti-islet autoantibodies destroy the islet cells of the pancreas that secrete insulin hormone. Type 1 diabetes mellitus was formerly ...

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Dry Eye, Autoimmune (Keratoconjunctivitis Sicca)

What Is Keratoconjunctivitis Sicca? Keratoconjunctivitis sicca is a distressing autoimmune form of dry eye that causes chronic bilateral dessication (dryness of both eyes) with inflammation of the conjunctiva and cornea due to tear abnormality. Little sores develop that cause the symptoms and ...

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Epilepsy (Convulsions)

epilepsy brain gluten celiac symptoms

What Is Epilepsy? Epilepsy is a dysfunctional disorder of the brain characterized by recurring seizures also called convulsions. Q: What happens in a seizure? A: During a seizure  abnormal electrical discharges occur within the brain. Not all seizures have the same intensity ...

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Erythema Nodosum 

What Is Erythema Nodosum? Erythema nodosum is an inflammatory disorder involving the deep dermis layer of skin and subcutaneous fat septa that underlies the skin. It is characterized by eruptions of recurrent or persistent multiple painful, red nodules under the skin that ...

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Erythroblastopenia, Transient

What Is Transient Erythroblastopenia? Transient erythroblastopenia is a rare disorder of red blood cell formation characterized by brief, reversible disappearance of erythroblasts (red blood cell precursors) in the bone marrow of children. Q: What do the red blood cells look ...

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