BioLineRx Ltd, a biopharmaceutical development company, was invited to deliver an oral presentation at the recent 2013 National Education Conference & Gluten-Free Expo, the Celiac Disease Foundation’s annual conference, in Pasadena, California.
Leah Klapper, Ph.D., General Manager, BioLine Innovations Jerusalem, presented BioLineRx’s therapy, BL-7010, for the treatment of celiac, as part of a session entitled Breaking Therapies Beyond the Gluten-Free Diet.
Being gluten free means adapting a whole new relationship to food, something that shapes our every day lives, holidays and traditions. Considering how complicated and challenging being gluten free can be, it seems appropriate to make our New Year’s Resolutions at least related to improving our health and gluten free lifestyle.
Just last week BioLineRx, a biopharmaceutical development company announced successful pre-clinical testing of a potentially revolutionary treatment for celiac disease. This new treatment may help celiac disease patients reduce their gluten toxins to create an overall healthy body for all celiac disease patients.
Jerusalem, Israel – February 21, 2012 – BioLineRx (NASDAQ: BLRX; TASE: BLRX), a biopharmaceutical development company, announced the publication of pre-clinical results demonstrating that BL-7010, an orally available treatment for celiac disease, reduces gluten toxicity (the negative effect of gluten on the patient’s body). The research was published in the February edition of Gastroenterology.
The findings indicate that BL-7010 (previously called P(HEMA-co-SS)) reduces digestion of wheat gluten, thereby decreasing its (more…)
There are a number of nutrient deficiencies associated with Celiac and other autoimmune disorders. These occur not only BEFORE diagnosis, due to flattened villi and malabsorption, but AFTER diagnosis as well. It’s up to us to choose healthy, naturally gluten-free foods (like fruits, veggies, lean protein and brown rice) in order to feel the best we can. Even then, we may still have deficiencies.
I was diagnosed about 5 years ago. Although I have experienced dramatic improvements in my health, sleep quality, and energy level, I have still been dealing with some “weird” symptoms that I wasn’t sure were going to go away. These include eye floaters (which I’ve noticed for about 2 years now), shakiness and rapid pulse especially during the first half of the day, and carbohydrate intolerance. (Eating high carb meals have been giving me headaches). So…. I was VERY excited when I heard that Gluten Free Works was going to be offering NUTRITION TESTING. I couldn’t wait to try it out.
When I got my results back, I was AMAZED at how many nutrient deficiencies I still had after being Gluten-Free for this many years. I came up deficient in:
VITAMIN A (this explained the eye floaters) CHROMIUM (I had never heard of chromium before now, but this explained my problem with carbs. I have since read that a deficiency in Chromium leads to DIABETES… so I’m glad I figured this out now, rather than later ;) SELENIUM (had never heard of that one either) (more…)
On December 13, I posted a question on the Glutenfreeworks Facebook page to ask people who had adopted a gluten-free diet if they no longer needed medications they had been taking. The response was incredible. Dozens of people described how they no longer needed drugs, some of which they had been taking for years or decades.
Here is my post and their responses…
“I gave a presentation to a group and mentioned a friend who had been on Zantac for 20 years. I went on to say that once she went gluten-free the acid reflux disappeared. A woman in the audience stood up and said the same thing happened to her – she had been on it since she was 10 (I’m guessing she was in her mid to late 30s.).
My question for you is what medication (of any kind) were you on, before you went gluten-free, that you no longer need to take and how long did it take before you did not need it anymore?”
LEXINGTON, Mass., Dec. 13, 2011 /PRNewswire/ – Avaxia Biologics, Inc., a privately-held biotech company developing oral antibody drugs that act locally within the gastrointestinal tract, announced today that the company was awarded U.S. Patent 8,071,101, “Antibody Therapy for Treatment of Diseases Associated With Gluten Intolerance.”
This patent, which expires on May 27, 2029, provides broad coverage for treating celiac disease using (more…)
In the summer of 2008 when the term “gluten” first entered my realm of awareness, I was enjoying a lifetime of excellent health except for the occasional cold or flu. In the summer of 2009 I was devastated to be diagnosed with a chronic and progressive kidney disease called Focal Segmental Glomerulosclerosis (or simply, FSGS) w/nephrotic syndrome. Like celiac disease, FSGS is an inflammatory disease, enflaming and scarring the glomeruli, or filtering system, of the kidneys. It was also that summer that I discovered that eliminating gluten from my diet put my disease into spontaneous, full remission, an extremely rare occurrence. I am on no medication, and have better health than ever before. Because of my fortune of getting my life back in short order, I want to share my experience with others so that others can be aware that eating gluten free does not only benefit those with celiac disease.
How did I get so lucky to go from health to serious illness back to health in a short period of time? (more…)
ScienceDaily (July 22, 2010) — Walter and Eliza Hall Institute scientists have identified the three protein fragments that make gluten — the main protein in wheat, rye and barley — toxic to people with coeliac disease.
Professor Bob Anderson from the Walter and Eliza Hall Institute in Melbourne, Australia, has identified the three protein fragments that make gluten -- the main protein in wheat, rye and barley -- toxic to people with celiac disease. (Credit: Czesia Markiewicz, Walter and Eliza Hall Institute)
Their discovery opens the way for a new generation of diagnostics, treatments, prevention strategies and food tests for the millions of people worldwide with coeliac disease.
When people with coeliac disease eat products containing gluten their body’s immune response is switched on and the lining of the small intestine is damaged, hampering their ability to absorb nutrients. The disease is currently treated by permanently removing gluten from the patient’s diet.
Dr Bob Anderson, head of the Walter and Eliza Hall Institute’s coeliac disease research laboratory, said it had been 60 years since gluten was discovered to be the environmental cause of coeliac disease.
“In the years since, the holy grail in coeliac disease research has been to identify the toxic peptide components of gluten; and that’s what we’ve done,” Dr Anderson said.
The research, done in collaboration with Dr Jason Tye-Din, Dr James Dromey, Dr Stuart Mannering, Dr Jessica Stewart and Dr Tim Beissbarth from the institute as well as Professor Jamie Rossjohn at Monash University and Professor Jim McCluskey at the University of Melbourne, is published in the journalScience Translational Medicine.
Dr. Bob Anderson & John Libonati at an NFCA-sponsored event April 30, 2009 in Philadelphia, USA where Dr. Anderson described his research and vaccine.
The study was started by Professor Anderson nine years ago and has involved researchers in Australia and the UK as well as more than 200 coeliac disease patients.
The patients, recruited through the Coeliac Society of Victoria and the Coeliac Clinic at John Radcliffe Hospital, UK, ate bread, rye muffins or boiled barley. Six days later, blood samples were taken to measure the strength of the patients’ immune responses to 2700 different gluten fragments. The responses identified 90 fragments as causing some level of immune reaction, but three gluten fragments (peptides) were revealed as being particularly toxic.
“These three components account for the majority of the immune response to gluten that is observed in people with coeliac disease,” Dr Anderson said. (more…)
Identifying celiac disease may seem simple enough. After all, there are tests your doctor can perform to determine if your body is reacting to gluten, the grain protein that those with celiac disease cannot tolerate. However, it is becoming more and more accepted that celiac disease may not always present as classic gut symptoms. Instead, celiac disease can cause and contribute to other diseases, deficiencies, ailments, and conditions.Because of this, some people with celiac disease may be diagnosed with diseases that could have been prevented or can be eliminated by a simple gluten-free diet. In other words, celiac is often considered the “root cause” of other conditions, even though it is seldom tested for in chronically-ill people.(more…)
If you or someone you know has a child with a mental illness, behavioral problem or unexplained neurological issue, you must watch these videos. They vividly illustrate how gluten and celiac disease can cause neurological illnesses and how removing gluten and casein from the diet can improve or cure the child.
Eamon Murphy started exhibiting mental aberrations and problems eating at three months of age. By the time he was three, his parents were frantically trying to understand what had caused his developmental delay in walking and talking, and now his trances, seizure-like episodes and regression. After a determined effort by his mother and a series of extraordinarily lucky events, he was finally diagnosed with celiac disease…and FULLY RECOVERED.
Watch these videos NOW and then forward this message to everyone you know with a child with a similar mental illness and their healthcare providers…because it is unacceptable that any child should be unnecessarily consigned to a life of suffering and diminished potential when a simple change in diet may cure them.
Eamon is totally normal now. If he had not been diagnosed, it is easy to see how he could have become incapacitated within a few years as his body and mind became sicker and sicker. Eventually, he may have been labeled autistic or schizophrenic. He may just have been called odd and slow.
Was it a miracle that Eamon recovered? No. It was a miracle that Eamon was diagnosed…
Here are some facts:
Autism affects 1 in 150 children. Medical experts recommend behavioral management and specialized speech, physical and occupational therapies (costing an estimated $70,000 per year per child), medications, community support and parental training.
Medical experts recommend AGAINST dietary intervention, yet the gluten-free/casein-free diet that helped Eamon has been demonstrated in thousands of cases to improve or resolve symptoms.
Celiac disease is still considered a rare gastrointestinal disorder that affects children by the majority of health professionals. In reality, celiac disease affects 1 in 100 people of any age, classifying it an epidemic by NIH standards. More people have celiac disease than Type 1 diabetes, breast cancer or autism. Diagnosis of celiac disease is estimated to take up to 11 years from first presentation of symptoms. Only 5% of people with celiac disease are estimated to be diagnosed.
Gastrointestinal problems occur in about 20% of people with celiac disease whereas neurological problems have been seen in as high as 51% at time of diagnosis.
The treatment for celiac disease is removing gluten from the diet and correcting nutrient deficiencies and any complications that have developed.
Unless you have symptoms that doctors expect to see – chronic diarrhea, failure to thrive, abdominal bloating and pain, and anemia – your likelihood of being diagnosed is extremely low.
For a complete list of symptoms related to celiac disease including dozens of neurological issues and problems in childhood, visit Gluten Free Works.
An excellent resource that outlines over 300 signs and symptoms and explains the relationship between celiac disease and the nutrient deficiencies that cause them is the book Recognizing Celiac Disease, by Cleo Libonati, RN, BSN. Recognizing Celiac Disease was endorsed by Dr. Peter Green, the director of the Celiac Disease Center at Columbia University who diagnosed Eamon Murphy.