Posts Tagged ‘Research’

 


biolinerx celiac disease therapy

BioLineRx Therapy BL – 7010 Treats Celiac Disease & Gluten Sensitivity

BioLineRx Ltd, a biopharmaceutical development company, was invited to deliver an oral presentation at the recent 2013 National Education Conference & Gluten-Free Expo, the Celiac Disease Foundation’s annual conference, in Pasadena, California.

Leah Klapper, Ph.D., General Manager, BioLine Innovations Jerusalem, presented BioLineRx’s therapy, BL-7010, for the treatment of celiac, as part of a session entitled Breaking Therapies Beyond the Gluten-Free Diet.

BL-7010 will be presented at (more…)


Teri Gruss, MS

Arsenic in Rice and Gluten Free Diets

December 10th, 2012 by Teri Gruss, MS

Rice, arsenic and gluten free diets

Arsenic in Rice and Gluten Free Diets Copyright (c) 2012 Teri Gruss

Do gluten-free diets put people at a higher risk for excessive and dangerous exposure to inorganic arsenic, a known carcinogen? It depends on the food choices you make and how much, and what variety of rice you eat.

In their ongoing analysis of arsenic in our food supply, Consumer Reports researchers analyzed 223 samples of rice and rice based products typically found at grocery stores in the U.S. Consumer Reports is a non-profit, independent consumer safety organization founded in 1936.

The results of Consumer Reports magazine analysis were recently published in the November 2012 issue, Arsenic in Your Food. Virtually all rice products tested contained arsenic, from low levels to potentially toxic levels.

What is arsenic and how can eating it hurt us? (more…)

gluten overweight weight gainLately, it seems like more and more celebrities and professional athletes are openly talking about going gluten free. Whether it’s due to a diagnosis of celiac disease or a gluten sensitivity, or simply because they want to get healthy, many of them have noted a weight loss as part of the benefits they’ve been seeing. Then why is it, that so many doctors and specialists will dismiss a diagnosis of celiac disease in a patient simply because the patient is not underweight?

In a recent article by Sonia Kupfer, MD, the belief that people with un-diagnosed celiac disease are all underweight is revealed to  (more…)

John Libonati Gluten Free Works

Weight loss, fad, miracle cure…there is an enormous amount of misinformation concerning the gluten-free diet in the news, on the internet and even in the medical community.

One of the worst ideas being perpetuated is that following a gluten-free diet can somehow be bad for you.

Dr. Stefano Guandalini, Founder and Medical Director of Columbia University’s Celiac Disease Center, answers the important question – Could following a gluten-free diet lead to other diseases?

(more…)

Gluten Free Works Jennifer Harris

Olmesartan Benicar Villous Atrophy Celiac DiseaseI just received an email from the Celiac Disease Research Center at Columbia University regarding a study showing a possible association between a blood pressure medication and villous atrophy. The blood pressure medication is called olmesartan and it is also known as Benicar, Benicar HCT, Azor, and Olmetec.

According to this article, the three-year study was conducted by the Mayo Clinic in Rochester, Minnesota and it included 22 patients who had symptoms of celiac disease, but antibody blood tests did not support that diagnosis. During this study patients improved with discontinuation of the drug, while a gluten-free diet had had no impact on their (more…)

There is no cure for celiac disease. But, there may soon be a new therapy to go along with a gluten-free diet.

A Phase II medical research study to test a potential therapy for people with celiac disease is underway and signing up participants at CeliacTrial.com.

celiac disease fasano

Alessio Fasano, MD. Co-founder of Alba Therapeutics

The investigational drug, Larazotide Acetate, was developed by Alba Therapeutics. It passed Phase I trials and is now being studied to determine how effective it is in different doses and whether side effects develop. Alba Therapeutics was co-founded by celiac disease researcher, Dr. Alessio Fasano, director of the Celiac Disease Center at the University of Maryland.1

The therapy is based on Dr. Fasano’s discovery that tight junctions between cells in the intestine can be opened or closed and that gluten relaxes these junctions. It is this process that leads to gluten improperly crossing into the body, thereby eliciting an immune reaction that leads to inflammation and damage characteristic of celiac disease.

“The reality is that the paracellular space is a gate, not a wall or fence. And if material gets through that space – even if it is only 1 to 5% of what normally travels through the cell – it could be associated with disease.”
-Alessio Fasano, MD1

Dr. Fasano discovered the potentially therapeutic utility of down-regulating intestinal permeability of celiac disease.1 In other words, he discovered that (more…)

Jennifer Harris

Shocking Facts About Celiac Disease

May 10th, 2012 by Jennifer Harris

celiac awareness month

Photo credit: Celiac Disease Awareness Month

May is National Celiac Disease Awareness Month, so it seems appropriate to share some medical facts about this autoimmune disease that just might shock you.

These facts come from Dr. Tom O’Bryan who is is a nationally recognized speaker and workshop leader specializing in gluten sensitivity and celiac disease.  Dr. O’Bryan’s specialty is in teaching the many manifestations of gluten sensitivity and celiac disease as they occur inside and outside of the (more…)

Gluten Free Works Jennifer Harris

(Editor’s Note: This study is closed.)

I just learned of a new study being conducted by The National Foundation for Celiac Awareness (NFCA) and Beth Israel Deaconess Medical Center (BIDMC) in Boston, Massachusetts to better understand the attitudes and beliefs of family members of persons with celiac disease.

More information on the study and how you can get involved follows: 

Celiac disease occurs in 10% of first-degree family members, such as a parent or sibling, and up to 20% of second-degree family members, such as an aunt, uncle or

Kelly Clayton Gluten Free Works

Imagine having the power to speak your mind. While you may be thinking to yourself that you already do speak your mind, I am talking about the power to tell every doctor in the world one thing.  We asked our Facebook followers the following:

“If you could tell every doctor on the planet one thing, what would it be?”

After 19 comments, the top three things that would be said to every doctor in the world were: listen to their patients, trust what patients are saying and know more about food allergies.

Listening to your patients

Such a simple idea: listening. It is amazing that many doctors do not listen to their patients, or pretend to listen.  Patients spend much time listening and mulling over what their doctors say, so why can’t doctors return the favor? Facebook follower Jenn Rheaume said, (more…)

Kelly Clayton Gluten Free Works

Just last week BioLineRx, a biopharmaceutical development company announced successful pre-clinical testing of a potentially revolutionary treatment for celiac disease.  This new treatment may help celiac disease patients reduce their gluten toxins to create an overall healthy body for all celiac disease patients.

Jerusalem, Israel – February 21, 2012 – BioLineRx (NASDAQ: BLRX; TASE: BLRX), a biopharmaceutical development company, announced the publication of pre-clinical results demonstrating that BL-7010, an orally available treatment for celiac disease, reduces gluten toxicity (the negative effect of gluten on the patient’s body). The research was published in the February edition of Gastroenterology.

The findings indicate that BL-7010 (previously called P(HEMA-co-SS)) reduces digestion of wheat gluten, thereby decreasing its (more…)